Pediatric Neurosurgery
Case Report
Successful Multimodal Therapies for a Primary Atypical Teratoid/Rhabdoid Tumor in the Cervical SpineYano S. · Hida K. · Kobayashi H. · Iwasaki Y.Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan
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Article / Publication Details
Received: May 21, 2007
Accepted: February 05, 2008
Published online: August 15, 2008
Issue release date: August 2008
Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 2
ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)
For additional information: https://www.karger.com/PNE
Abstract
Atypical teratoid/rhabdoid tumor (AT/RT) occurring in the central nervous system is a high-grade malignant tumor, and its prognosis is poor for patients younger than 3 years of age. In this article, we present a case of infant AT/RT in the cervical spine and its successful treatment by intensive chemotherapy. The patient, a 1.75-year-old girl, developed an acute, progressive tetraparesis. MRI revealed a large, intradural mass in the cervical spine.Total surgical resection was performed, and the specimen was diagnosed as AT/RT. Continuously, she received intensive chemotherapy using thiotepa with autologous bone marrow transplantation. At the age of nearly 3 years, she received radiation therapy to the local tumor bed and craniospinal axis. She is now 4 years old and has been maintained in complete remission with a good clinical course and no neurological deficit. The success of this treatment for the patient was that we could prevent tumor recurrence until she was able to receive radiotherapy.
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Article / Publication Details
Received: May 21, 2007
Accepted: February 05, 2008
Published online: August 15, 2008
Issue release date: August 2008
Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 2
ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)
For additional information: https://www.karger.com/PNE
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