Human Heredity
Original Paper
Isoelectric Focusing of Human PhosphoglucomutaseData on the Distribution of Variant Phenotypes in Three Population Samples from South West France Centre d’Hémotypologie du CNRS, CHU de Purpan, Toulouse, France
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Article / Publication Details
Published online: November 24, 2010
Issue release date: 1981
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5652 (Print)
eISSN: 1423-0062 (Online)
For additional information: https://www.karger.com/HHE
Abstract
Leukocyte lysates obtained from blood specimens of individuals from Central and Western Pyrenean groups (Barèges and Basques) and from the population of Toulouse city have been typed for PGMa1 isozymes using isoelectric focusing (pH range: 3–9.5) in polyacrylamide gels. The determination of usual PGM1 phenotypes was simultaneously performed on red cells by starch gel electrophoresis. Significant differences were found between the three communities. In Barèges samples only 6 of the 10 phenotypes known at PGMa1 locus have been observed. In the same group, 36 mating types were studied in distinct families. The segregation on the phenotypes is in agreement with the codominant inheritance of the alleles. In Basques the gene frequencies showed intermediate values between Toulouse and Barèges. PGMa21 reaches a higher frequency in the latter community (0.306). In the Toulouse population sample the results are comparable with those previously published in western Europeans.
© 1981 S. Karger AG, Basel
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Article / Publication Details
Published online: November 24, 2010
Issue release date: 1981
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5652 (Print)
eISSN: 1423-0062 (Online)
For additional information: https://www.karger.com/HHE
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