Human Heredity

Original Paper

Genetic Linkage Studies of Transferrin, Pseudocholinesterase, and Chromosome 1 Loci

Sparkes R.S.a,b,c · Field L.L.b,c · Sparkes M.C.a,b,c · Crist M.a · Spence M.A.b,c,d · James K.e · Garry P.J.f

Author affiliations

aDepartments of Medicine and Pediatrics, bMental Retardation Research Center, cDepartment of Psychiatry, and dDepartment of Biomathematics, UCLA, Los Angeles, Calif.; eDepartment of Immunology, Presbyterian-St. Luke’s Hospital, Chicago, 111.; fClinical Nutrition Laboratory, University of New Mexico, Albuquerque, N.Mex., USA

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Hum Hered 1984;34:96–100

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: September 02, 2008
Issue release date: 1984

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0001-5652 (Print)
eISSN: 1423-0062 (Online)

For additional information: https://www.karger.com/HHE

Abstract

Genetic linkage analysis of a pedigree with four different alleles for pseudocholinesterase (CHEl) gives a positive lod score of 0.37 at Θ= 0.16 for linkage with transferrin (TF), a finding which supports previous reports of linkage between CHEl and TF. Evaluation of linkage relations of CHEl and TF using unreported families from our data bank fails to establish linkage with chromosome 1 loci (6-PGD, Rh, PGM1, AMY2 and FY). These results are consistent with recent studies which suggest that TF is on human chromosome 3.

© 1984 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: September 02, 2008
Issue release date: 1984

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0001-5652 (Print)
eISSN: 1423-0062 (Online)

For additional information: https://www.karger.com/HHE


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