Human Heredity
Short Communication
Pi MZ Phenotype and an Increased Prevalence of Reported Psoriasis in a Community SurveyHorne S.L.a · Junk G.J.b · Cockcroft D.W.a · Lovegrove A.a · Dosman J.A.aaSection of Respiratory Medicine, University of Saskatchewan, Saskatoon, Sask., bHumboldt, Sask., Canada
Keywords: α1-AntitrypsinPi typePsoriasis |
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Article / Publication Details
Published online: September 02, 2008
Issue release date: 1986
Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5652 (Print)
eISSN: 1423-0062 (Online)
For additional information: https://www.karger.com/HHE
Abstract
In a community survey of 953 adults we identified 40 who reported having had psoriasis. Eight of these cases were subsequently documented from physicians’ records. α1-Antitrypsin (α1-AT) phenotyping identified 35 MZ individuals, 4 (11.4%) of whom reported psoriasis. Among the 918 non-MZ individuals 36 (3.9%) reported psoriasis, yielding a relative incidence of 3.2 (p < 0.05). This is consistent with previous reports suggesting an association between moderate α1-AT deficiency and psoriasis.
© 1986 S. Karger AG, Basel
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Article / Publication Details
Published online: September 02, 2008
Issue release date: 1986
Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5652 (Print)
eISSN: 1423-0062 (Online)
For additional information: https://www.karger.com/HHE
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