Cerebrovascular Diseases

Original Paper

Trends in Risk Factors, Stroke Subtypes and Outcome

Nineteen-Year Data from the Sagrat Cor Hospital of Barcelona Stroke Registry

Arboix A.a · Cendrós V.a · Besa M.a · García-Eroles L.b · Oliveres M.a · Targa C.a · Balcells M.a · Comes E.a · Massons J.a

Author affiliations

aDepartment of Neurology, Cerebrovascular Division, Hospital Universitari del Sagrat Cor, Universitat de Barcelona, Barcelona, and bClinical Information Systems, Hospital Universitari de Bellvitge, L’Hospitalet de Llobregat, Spain

Keywords: Registries, statistics, numerical dataBrain ischemia, epidemiologyIntracranial hemorrhages, epidemiologyStroke, epidemiologyComparative study

Related Articles for ""
Cerebrovasc Dis 2008;26:509–516
https://doi.org/10.1159/000155989

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 22, 2008
Accepted: June 02, 2008
Published online: September 23, 2008
Issue release date: November 2008

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 5

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: https://www.karger.com/CED

Abstract

Background: Prospective stroke registries allow analyzing important aspects of the natural history of acute cerebrovascular events. Using the Sagrat Cor Hospital of Barcelona Stroke Registry, we aimed to determine trends in risk factors, stroke subtypes, prognosis and in-hospital mortality over 19 years in hospitalized stroke patients. Methods: The study population consisted of 2,416 first-ever stroke patients (ischemic stroke, n = 2,028; intracerebral hemorrhage, n = 334) included in the stroke registry up to December 31, 2004. Temporal trends in stroke patient characteristics for the periods 1986–1992, 1993–1998 and 1999–2004 were assessed. Results: Age was significantly different among the analyzed periods (p < 0.001), showing an increment in older patients throughout time. Hypertension (p = 0.001), diabetes (p = 0.004), ischemic heart disease (p = 0.002) and atrial fibrillation increased (p = 0.000) as opposed to heavy smoking (p = 0.000) and history of TIA (p = 0.025). The mortality rate and the length of hospital stay decreased (p = 0.001), whereas transfer to convalescent/rehabilitation units increased (p = 0.001). Conclusions: An improvement in acute-stroke management and possibly evolution of cerebrovascular risk factors is reflected by changes in the risk factors and outcome of first-ever stroke patients admitted to a stroke unit over a 19-year time span.

© 2008 S. Karger AG, Basel



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References

  1. Mohr JP: Stroke data banks. Stroke 1986;17:171–172.
    External Resources
  2. Foulkes MA, Wolf PA, Price TR, Mohr JP, Hier DB: The Stroke Data Bank: design, methods, and baseline characteristics. Stroke 1988;19:547–554.
    External Resources
  3. Carrera E, Maeder-Ingvar M, Rossetti AO, Devuyst G, Bogousslavsky J: Trends in risk factors, patterns and causes in hospitalized strokes over 25 years: The Lausanne Stroke Registry. Cerebrovasc Dis 2007;24:97–103.
    External Resources
  4. Arboix A, Morcillo C, García-Erols L, Oliveres M, Massons J, Targa C: Different vascular risk factor profiles in ischemic stroke subtypes: a study from the ‘Sagrat Cor Hospital of Barcelona Stroke Registry’. Acta Neurol Scand 2000;102:264–270.
    External Resources
  5. Arboix A, Oliveres M, Massons J, Pujades R, García-Eroles L: Early differentiation of cardioembolic from atherothrombotic cerebral infarction: a multivariate analysis. Eur J Neurol 1999;6:677–683.
    External Resources
  6. Arboix A, Font A, Garro C, García-Eroles L, Comes E, Massons J: Recurrent lacunar infarction following a previous lacunar stroke: a clinical study of 122 patients. J Neurol Neurosurg Psychiatry 2007;78:1392–1394.
    External Resources
  7. Arboix A, Bechich S, Oliveres M, García-Eroles L, Massons J, Targa C: Ischemic stroke of unusual cause: clinical features, etiology and outcome. Eur J Neurol 2001;8:133–139.
    External Resources
  8. Arboix A, Alvarez-Sabín J, Soler L, Cerebrovascular Study Group of the Spanish Society of Neurology: Nomenclatura de las enfermedades vasculares cerebrales. Neurología 1998;13(suppl 1):1–10.
  9. Special Report from the National Institute of Neurological Disorders and Stroke: classification of cerebrovascular diseases. III. Stroke 1990;21:637–676.
    External Resources
  10. Grupo de Estudio de las Enfermedades Cerebrovasculares de la Sociedad Española de Neurología: Manejo del paciente con enfermedad vascular cerebral aguda. Recomendaciones 1992. Barcelona, Edos 1992.
  11. Silver FL, Norris JW, Lewis AJ, Hachinski VC: Early mortality following stroke: a prospective review. Stroke 1984;15:492–496.
    External Resources
  12. Armitage P: Statistical Methods in Medical Research. New York, Wiley, 1977.
  13. Arboix A, Miguel M, Císcar E, García-Eroles L, Massons J, Balcells M: Cardiovascular risk factors in patients aged 85 or older with ischemic stroke. Clin Neurol Neurosurg 2006;108:638–643.
    External Resources
  14. Arboix A: Increasing relevance of acute cerebrovascular disease in very old patients (editorial). Eur J Neurol 2007;14:833–834.
    External Resources
  15. Arboix A, Oliveres M, García-Eroles L, Maragall C, Massons J, Targa C: Acute cerebrovascular disease in women. Eur Neurol 2001;145:199–205.
    External Resources
  16. Arboix A, Milian M, Oliveres M, Garcia-Eroles L, Massons J: Impact of female gender on prognosis of type 2 diabetic patients with ischemic stroke. Eur Neurol 2006;56:6–12.
    External Resources
  17. 1999 World Health Organisation-International Society of Hypertension Guidelines for the Management of Hypertension. J Hypertens 1999;17:151–183.
    External Resources
  18. Arenillas JF, Moro MA, Dávalos A: The metabolic syndrome and stroke. Potential treatment approaches. Stroke 2007;38:2196–2203.
    External Resources
  19. Whisnant JP: Modeling of risk factors for ischemic stroke: The Willis Lecture. Stroke 1997;28:1840–1844.
    External Resources
  20. Helgason CM, Wolf PA: American Heart Association Prevention Conference IV – prevention and rehabilitation of stroke: executive summary. Circulation 1997;96:701–707.
    External Resources
  21. Wolf PA, Abott RD, Kannel WB: Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:983–988.
    External Resources
  22. Benavente O, White CL, Roldan AM: Small vessel strokes. Curr Cardiol Rep 2005;7:23–28.
    External Resources
  23. Bornstein N, Aronovich BD, Karepov VG, Gur AY, Treves TA, Oved M, Korczyn AD: The Tel Aviv Stroke Registry: 3600 consecutive patients. Stroke 1996;27:1770–1773.
    External Resources
  24. Yip P-K, Jeng JS, Lee TK, Chang YC, Huang ZS, Ng SK, Chen RC: Subtypes of ischemic stroke: a hospital-based registry in Taiwan (SCAN-IV). Stroke 1997;28:2507–2512.
    External Resources
  25. Moulin T, Tatu L, Crépin-Leblond T, Chavot D, Bergès S, Rumbach L: The Besançon Stroke Registry: an acute stroke registry of 2500 consecutive patients. Eur Neurol 1997;38:10–20.
    External Resources
  26. Kumral E, Özkaya B, Sagduyu A, Sirin H, Vardarli E, Pehlivan M: The Ege Stroke Registry: a hospital-based study in the Aegean Region, Izmir, Turkey – analysis of 2000 stroke patients. Cerebrovasc Dis 1998;8:278–288.
    External Resources
  27. Frey JL, Jahnke HK, Bulfinch EW: Differences in stroke between white, Hispanic, and Native American patients: the Barrow Neurological Institute stroke database. Stroke 1998;29:29–33.
    External Resources
  28. Martí-Vilalta JL, Arboix A: The Barcelona Stroke Registry. Eur Neurol 1999;41:135–142.
    External Resources
  29. Stewart JA, Dundas R, Howard RS, Rudd AG, Wolf CD: Ethnic differences in incidence of stroke: prospective study with stroke register. BMJ 1999;318:967–971.
    External Resources
  30. Vemmos KN, Bots ML, Tsibouris PK, Zis VP, Grobbee DE, Stranjalis GS, Stamatelopoulos S: Stroke incidence and case fatality in Southern Greece: the Arcadia Stroke Registry. Stroke 1999;30:363–370.
    External Resources
  31. Vemmos DN, Takis CE, Georgilis K, Zakopoulos NA, Lekakis JP, Papamichael CM, Zis VP, Stamatelopoulos S: The Athens Stroke Registry: results of a five-year hospital-based study. Cerebrovasc Dis 2000;10:133–141.
    External Resources
  32. Thrift AG, Dewey HM, Macdonell RA, McNeil JJ, Donnan GA: Stroke incidence on the East Coast of Australia: the North East Melbourne Stroke Incidence Study (NEMESIS). Stroke 2000;31:2087–2092.
    External Resources
  33. Arboix A, Massons J, Oliveres M, Garcia L, Titus F: An analysis of 1000 consecutive patients with acute cerebrovascular disease: the registry of cerebrovascular diseases of La Alianza-Hospital Central of Barcelona (article in Spanish). Med Clin (Barc) 1993;101:281–285.
    External Resources
  34. Lee BI, Nam HS, Heo JH, Kim DI; Yonsei Stroke Team: Yonsei Stroke Registry: analysis of 1000 patients with acute cerebral infarctions. Cerebrovasc Dis 2001;12:145–151.
    External Resources
  35. Grau AJ, Weimar C, Buggle F, Heinrich A, Foertler M, Neumaier S, Glahn J, Brandt T, Hacke W, Diener HC: Risk factors, outcome, and treatment in subtypes of ischemic stroke: the German Stroke Data Bank. Stroke2001;32:2559–2599.
    External Resources
  36. Kaul S, Sunitha P, Suvarna A, Meena AK, Uma M, Reddy JM: Subtypes of ischemic stroke in a metropolitan city of South India (one-year data from a hospital-based stroke registry). Neurol India 2002;50:S8–S14.
    External Resources
  37. Wang Y, Levi Ch R, Attia JR, D’Este CA, Spratt N, Fisher J: Seasonal variation in stroke in the Hunter Region, Australia: a 5-year hospital-based study, 1995–2000. Stroke 2003;34:1144–1150.
    External Resources
  38. Corbin DO, Poddar V, Hennis A, Gaskin A, Rambarat C, Wilks R, Wolfe CD, Fraser HS: Incidence and case fatality rates of first-ever stroke in a black Caribbean population: the Barbados Register of Strokes. Stroke 2004;35:1254–1258.
    External Resources
  39. Kapral MK, Laupacis A, Phillips SJ, Silver FL, Hill MD, Fang J, Richards J, Tu JV; Registry of the Canadian Stroke Network: Stroke care delivery in institutions participating in the Registry of the Canadian Stroke Network. Stroke 2004;35:1756–1762.
    External Resources
  40. Correia M, Silva MR, Matos I, Magalhães R, Lopes JC, Ferro JM, Silva MC: Prospective community-based study of stroke in the northern Portugal: incidence and case fatality in rural and urban populations. Stroke 2004;35:2048–2053.
    External Resources
  41. Caplan LR, Wityk RJ, Glass TA, Tapia J, Pazdera L, Chang HM, Teal P, Dashe JF, Chaves CJ, Breen JC, Vemmos K, Amarenco P, Tettenborn B, Leary M, Estol C, Dewitt LD, Pessin MS: New England Medical Center Posterior Circulation Registry. Ann Neurol 2004;56:389–398.
    External Resources
  42. Lee BC, Hwang SH, Jung S, Yu KH, Lee JH, Cho SJ, Lee SM, Song HK: The Hallym Stroke Registry: a web-based stroke data bank with an analysis of 1,654 consecutive patients with acute stroke. Eur Neurol 2005;54:81–87.
    External Resources
  43. Syme PD, Byrne AW, Chen R, Devenny R, Forbes JF: Community-based stroke incidence in a Scottish population: the Scottish Borders Stroke Study. Stroke 2005;36:1837–1843.
    External Resources
  44. Reeves MJ, Arora S, Broderick JP, Frankel M, Heinrich JP, Hickenbottom S, Karp H, LaBresh KA, Malarcher A, Mensah G, Moomaw CJ, Schwamm L, Weiss P; Paul Coverdell Prototype Registries Writing Group: Acute stroke care in the US: results from 4 pilot prototypes of the Paul Coverdell National Acute Stroke Registry. Stroke 2005;36:1232–1240.
    External Resources
  45. Liu X, Xu G, Wu W, Zhang R, Yin Q, Zhu W: Subtypes and one-year survival of first-ever stroke in Chinese patients: The Nanjing Stroke Registry. Cerebrovasc Dis 2006;22:130–136.
    External Resources
  46. Ghandehari K, Izadi Z: The Khorasan Stroke Registry: results of a five-year hospital-based study. Cerebrovasc Dis 2007;23:132–139.
    External Resources

Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 22, 2008
Accepted: June 02, 2008
Published online: September 23, 2008
Issue release date: November 2008

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 5

ISSN: 1015-9770 (Print)
eISSN: 1421-9786 (Online)

For additional information: https://www.karger.com/CED

Copyright / Drug Dosage / Disclaimer

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2008, Vol.26, No. 5

November 2008

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