Original Paper
Fatty Acid Profile of Human Milk of Portuguese Lactating Women: Prospective Study from the 1st to the 16th Week of LactationRibeiro M.a · Balcao V.c · Guimaraes H.a · Rocha G.a · Moutinho C.c · Matos C.c · Almeida C.c · Casal S.b · Guerra A.aaDepartment of Paediatrics, Hospital S. João, Faculty of Medicine, and bFaculty of Pharmaceutical Sciences, University of Porto, and cBioengineering and Pharmacoclinical Research Group, University of Fernando Pessoa, Porto, Portugal
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Ann Nutr Metab 2008;53:50–56
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Article / Publication Details
First-Page Preview
Received: May 05, 2006
Accepted: May 02, 2008
Published online: September 19, 2008
Issue release date: October 2008
Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 4
ISSN: 0250-6807 (Print)
eISSN: 1421-9697 (Online)
For additional information: https://www.karger.com/ANM
Abstract
Background/Aims: Fatty acid (FA) composition varies over the course of the day and during lactation. The aim of this study was to evaluate FA composition and its compositional stability in human milk, from day 7 to week 16 of lactation. Methods: Human milk was collected from all feedings over 24 h at day 7 and weeks 4, 8, 12 and 16 of lactation in 31 lactating women. FAs were analyzed through gas chromatography. Comparisons were made with analysis of variance. Results: Total monounsaturated FAs decreased from 33.04 ± 2.58% wt/wt at day 7 to 31.48 ± 3.32% wt/wt at week 16 of lactation, much at the expenses of the decrease in the major monounsaturated FA found in human milk, oleic acid. Main polyunsaturated FAs n-6 and n-3 showed fluctuations from day 7 up to week 16 of lactation, but with no statistical significance. Arachidonic acid significantly decreased from transitional to mature milk. Conclusions: The FA profile obtained throughout the study time points presented very low levels of oleic acid and very high linoleic acid/α-linoleic acid ratios which reflect recent changes in Portuguese women’s food patterns. Despite this, the ascorbate/dehydroascorbate ratio remained constant during the study, suggesting a protective metabolic mechanism.
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Article / Publication Details
First-Page Preview
Received: May 05, 2006
Accepted: May 02, 2008
Published online: September 19, 2008
Issue release date: October 2008
Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 4
ISSN: 0250-6807 (Print)
eISSN: 1421-9697 (Online)
For additional information: https://www.karger.com/ANM
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