Journal of Vascular Research
Resolution of Lipid-Containing Atherosclerotic Lesions Induced by InjuryMoore S. · Friedman R.J. · Gent M.Departments of Pathology and Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ont.
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Article / Publication Details
Received: April 02, 1976
Accepted: November 08, 1976
Published online: September 18, 2008
Issue release date: 1977
Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0
ISSN: 1018-1172 (Print)
eISSN: 1423-0135 (Online)
For additional information: https://www.karger.com/JVR
Abstract
In previous experiments, injury-induced atherosclerosis has been shown to be associated with the development of fatty streaks. The findings suggested that fatty streaks might represent a stage in healing of intimal injury evolving to fibrous plaques, free of lipid. The present experiment was designed to study the incidence and evolution of these lesions during a 2-week period of lesion retrogression following removal of a catheter placed in the aorta for 1 week. The findings indicate that as fat-containing lesions, either of the thromboatherosclerotic or fatty streak varieties, decreased, the amount of nonlipid-containing fibrous lesions increased.
© 1977 S. Karger AG, Basel
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Article / Publication Details
Received: April 02, 1976
Accepted: November 08, 1976
Published online: September 18, 2008
Issue release date: 1977
Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0
ISSN: 1018-1172 (Print)
eISSN: 1423-0135 (Online)
For additional information: https://www.karger.com/JVR
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