Psychological Intervention for Premenstrual Syndrome: A Meta-Analysis of Randomized Controlled TrialsBusse J.W.a · Montori V.M.d · Krasnik C.b · Patelis-Siotis I.c · Guyatt G.H.a ·
aDepartment of Clinical Epidemiology and Biostatistics, bDepartment of Medical Science, Psychiatry and Behavioural Neuroscience, and cDepartment of Psychiatry, McMaster University, Hamilton, Ont., Canada; dKnowledge and Encounter Research Unit, Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn., USA
Do you have an account?
- Rent for 48h to view
- Buy Cloud Access for unlimited viewing via different devices
- Synchronizing in the ReadCube Cloud
- Printing and saving restrictions apply
Rental: USD 8.50
Cloud: USD 20.00
Background: We conducted a systematic review and meta-analysis to determine the efficacy of psychological interventions for premenstrual syndrome. Methods: We systematically searched and selected studies that enrolled women with premenstrual syndrome in which investigators randomly assigned them to a psychological intervention or to a control intervention. Trials were included irrespective of their outcomes and, when possible, we conducted meta-analyses. Results: Nine randomized trials, of which 5 tested cognitive behavioural therapy, contributed data to the meta-analyses. Low quality evidence (design and implementation weaknesses of the studies, possible reporting bias) suggests that cognitive behavioural therapy significantly reduces both anxiety (effect size [ES] = –0.58; 95% confidence interval [CI] = –1.15 to –0.01; number needed to treat [NNT] = 5), and depression (ES = –0.55; 95% CI = –1.05 to –0.05; NNT = 5), and also suggests a possible beneficial effect on behavioural changes (ES = –0.70; 95% CI = –1.29 to –0.10; NNT = 4) and interference of symptoms on daily living (ES = –0.78; 95% CI = –1.53 to –0.03; NNT = 4). Results provide much more limited support for monitoring as a form of therapy and suggest the ineffectiveness of education. Conclusions: Low quality evidence from randomized trials suggests that cognitive behavioural therapy may have important beneficial effects in managing symptoms associated with premenstrual syndrome.
© 2008 S. Karger AG, Basel
Article / Publication Details
Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.