Pathobiology
Original Paper
Acute Encephalopathy Induced in Cats with a Stealth Virus Isolated from a Patient with Chronic Fatigue SyndromeMartin W.J.a · Glass R.T.baDepartment of Pathology, University of Southern California School of Medicine, Los Angeles, Calif, and bDepartments of Oral Pathology and Pathology, University of Oklahoma, Colleges of Dentistry and Medicine, Oklahoma City, Okla., USA
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Article / Publication Details
Received: June 10, 1995
Accepted: June 22, 1995
Published online: October 08, 2008
Issue release date: 1995
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 1015-2008 (Print)
eISSN: 1423-0291 (Online)
For additional information: https://www.karger.com/PAT
Abstract
A simian cytomegalovirus-related stealth virus, isolated from a patient with the chronic fatigue syndrome, induced an acute neurological illness when inoculated into cats. Histological examination of brain tissue showed foci of cells with cytoplasmic vacuolization and an absence of any inflammatory reaction. Electron microscopy confirmed the presence of herpes-like viral particles and viral-like products in the brain of an inoculated animal. These findings support the role of stealth viruses in the pathogenesis of human neurological diseases and provide an animal model to evaluate potential antiviral therapy.
© 1995 S. Karger AG, Basel
Article / Publication Details
Received: June 10, 1995
Accepted: June 22, 1995
Published online: October 08, 2008
Issue release date: 1995
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 1015-2008 (Print)
eISSN: 1423-0291 (Online)
For additional information: https://www.karger.com/PAT
Copyright / Drug Dosage / Disclaimer
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