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Original Paper

Strain–Related Acid Production by Oral Streptococci

de Soet J.J.a · Nyvad B.b · Kilian M.c

Author affiliations

aOral Microbiology Section, Department of Oral Biology, Academic Centre for Dentistry, Amsterdam, The Netherlands; bDepartment of Dental Pathology, Operative Dentistry and Endodontics, Royal Dental College, Aarhus, and cDepartment of Medical Microbiology and Immunology, University of Aarhus, Denmark

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Caries Res 2000;34:486–490

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: November 08, 2000
Issue release date: November – December

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 0

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: https://www.karger.com/CRE

Abstract

Acid production, in particular at low pH, is thought to be an important ecological determinant in dental caries. The aim of the present study was to determine the acid producing capability at different pH levels of 47 streptococcal strains, representing 9 species, isolated from human dental plaque. The bacteria were grown until mid log–phase under anaerobic conditions and acid production was measured in a pH–stat system at pH 7.0, 6.0, 5.5 and 5.0. At all pH values, the mean velocity of acid production (Vap) by Streptococcus mutans and S. sobrinus was significantly higher (p<0.01; ANOVA) than that of the other oral streptococci, including S. mitis, S. oralis, S. gordonii, S. sanguis, S. intermedius, S. anginosus, S. constellatus, and S. vestibularis. However, the Vap of some strains of S. mitis biovar 1 and S. oralis, particularly at pH values of 7.0 and 6.0, exceeded that of some strains of S. mutans. The Vap decreased with pH for all strains, but some strains of S. mitis biovar 1 and strains of the mutans streptococci maintained a relatively high rate of acid production. The results suggest that some strains of S. mitis biovar 1 and S. oralis may play an important role in caries development by modifying the environment in dental plaque to become favourable for the succession of aciduric species. The study furthermore emphasises the need for detailed species and biovar identification of oral streptococci and for recognition of the significant physiological differences that occur within single species.


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: November 08, 2000
Issue release date: November – December

Number of Print Pages: 5
Number of Figures: 2
Number of Tables: 0

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: https://www.karger.com/CRE


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