American Journal of Nephrology
Clinical Study
Solvent Nephrotoxicity in Humans and Experimental AnimalsNelson N.A.a,b · Robins T.G.b · Port F.K.cDepartments of aEpidemiology, bEnvironmental and Industrial Health, and cInternal Medicine, University of Michigan, Ann Arbor, Mich., USA
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Article / Publication Details
Received: January 17, 1989
Accepted: May 11, 1989
Published online: October 28, 2008
Issue release date: 1990
Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0
ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)
For additional information: https://www.karger.com/AJN
Abstract
Evidence from human case reports, epidemiologic studies and animal experiments have suggested that exposure to organic solvents is associated with a wide spectrum of renal disorders, including tubular necrosis, interstitial disease, glomerulonephritis and neoplasia. This review summarizes what is known about solvent-induced renal damage in humans and experimental animals, with emphasis on hypothesized mechanisms by which this broad range of disorders may occur.
© 1990 S. Karger AG, Basel
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Article / Publication Details
Received: January 17, 1989
Accepted: May 11, 1989
Published online: October 28, 2008
Issue release date: 1990
Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0
ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)
For additional information: https://www.karger.com/AJN
Copyright / Drug Dosage / Disclaimer
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