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Factors Predictive of Long-Term Coronary Heart Disease Mortality among 10,059 Male Israeli Civil Servants and Municipal Employees

A 23-Year Mortality Follow-Up in the Israeli Ischemic Heart Disease Study

Goldbourt U.a · Yaari S.b · Medalie J.H.c

Author affiliations

aDepartment of Epidemiology and Preventive Medicine, Sackler School of Medicine, Tel Aviv University, and Neufeld Cardiac Research Institute, Sheba Medical Center, Tel Hashomer, Israel; bBar-Ilan University Computing Center, Ramat Gan, Israel; cDivision of Research, Department of Family Medicine, Case Western Reserve University Medical School, Cleveland, Ohio, USA

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Cardiology 1993;82:100–121

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: November 14, 2008
Issue release date: 1993

Number of Print Pages: 22
Number of Figures: 0
Number of Tables: 0

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: http://www.karger.com/CRD

Abstract

Over 10,000 male civil servants and municipal employees in Israel, aged 40 years and above, underwent an extensive clinical, biochemical, anthropometric, sociodemographic and psychosocial evaluation in 1963, 1965 and 1968. Follow-up for mortality was continued through 1986. Over 23 years, a number of previously established risk factors for coronary heart disease (CHD) incidence were found to predict mortality. The long-term follow-up assisted in illustrating temporal patterns. A single casual assessment of blood pressure retained high prediction for long-term mortality. Blood lipids, while significantly associated with both coronary and all-cause mortality, exhibited a small contribution to the latter, when compared to hypertension, cigarette smoking habits and diabetes. Weak associations of long-term coronary mortality with the dietary intake patterns of fatty acids, as reported at baseline, were probably fully mediated by the effect of the diet on serum cholesterol. Religious orthodoxy appeared to provide a degree of immunity, part of which was independent of life-style correlates. A number of now well-established associations in cardiovascular epidemiology were first demonstrated, or amplified, in the study. Patterns of ethnic diversity in the risk factor and prevalence rates of CHD persisted, as viewed from the angle of mortality rates, over nearly a quarter of a decade, highlighting the enigma of a migrant country as a cardiovascular melting pot.

© 1993 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: November 14, 2008
Issue release date: 1993

Number of Print Pages: 22
Number of Figures: 0
Number of Tables: 0

ISSN: 0008-6312 (Print)
eISSN: 1421-9751 (Online)

For additional information: http://www.karger.com/CRD


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