Annals of Nutrition and Metabolism
Original Paper
Calcium Metabolism in the Lyon Hypertensive RatPernot F.a · Luthringer C.b · Vincent M.c · Sassard J.c · Berthelot A.b · Gairard A.aaPharmacologie Cellulaire et Moléculaire, CNRS UA 600, Université Louis-Pasteur, Strasbourg; bLaboratoire de Physiologie, Faculté de Médecine et de Pharmacie, Université de Franche-Comté, Besançon; cDépartement de Physiologie et Pharmacologie Clinique, CNRS UA 606, Université Claude-Bernard, Lyon, France
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Article / Publication Details
Received: January 20, 1990
Accepted: June 29, 1990
Published online: November 19, 2008
Issue release date: 1991
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 0250-6807 (Print)
eISSN: 1421-9697 (Online)
For additional information: https://www.karger.com/ANM
Abstract
In order to define relationships between hypertension and calcium metabolism, we have studied calcium metabolism in Lyon genetically hypertensive rats (LH) and their two normotensive controls (LN and LL). The total and ionized plasma calcium levels were slightly but significantly decreased in the LH compared to LN and LL from 4 to 23 weeks of age. During this period, dietary calcium intake was decreased in LH rats but urinary and fecal excretions did not differ. Intestinal utilization and balance were impaired during development of hypertension in LH rats. Thus minor alterations in calcium metabolism differentiate the LH rat from its normotensive controls.
© 1991 S. Karger AG, Basel
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Article / Publication Details
Received: January 20, 1990
Accepted: June 29, 1990
Published online: November 19, 2008
Issue release date: 1991
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 0250-6807 (Print)
eISSN: 1421-9697 (Online)
For additional information: https://www.karger.com/ANM
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