Hormone Research in Paediatrics
Original Paper
Prolactin Suppression and Spermatogenic Developments in Maturing Rats. A Quantitative StudyNag S.a · Sanyal S.a · Ghosh K.K.b · Biswas N.M.aaDepartment of Physiology, University of Calcutta; bDepartment of Biochemistry, Institute of Post-Graduate Medical Education and Research, Calcutta, India
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Article / Publication Details
Received: March 11, 1981
Accepted: August 21, 1981
Published online: November 25, 2008
Issue release date: 1981
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 1663-2818 (Print)
eISSN: 1663-2826 (Online)
For additional information: https://www.karger.com/HRP
Abstract
Prolonged suppression of prolactin (PRL) in immature male rats inhibits the spermatocyte-spermatid conversion process, alters Leydig cell morphology, decreases accessory sex organ weight and increases serum LH levels without a significant alteration in serum FSH concentration. Amelioration of these effects by exogenous PRL strongly indicates that in the absence of PRL excess titers of endogenous LH fail to exert an influence on the spermatogenic activity of maturing testes.
© 1981 S. Karger AG, Basel
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Article / Publication Details
Received: March 11, 1981
Accepted: August 21, 1981
Published online: November 25, 2008
Issue release date: 1981
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 1663-2818 (Print)
eISSN: 1663-2826 (Online)
For additional information: https://www.karger.com/HRP
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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