Nephron

Original Paper

A New Method for the Assessment of Bone Mass in Renal Osteodystrophy

Usefulness of Computerized Tomography in Hemodialysis Patients

Torres A. · Moya M.

Author affiliations

Service of Nephrology and Metabolic Unit, Hospital General y Clínico de Tenerife, Canary Islands, Spain

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Nephron 1982;30:231–236

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Accepted: July 30, 1981
Published online: December 03, 2008
Issue release date: 1982

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF

Abstract

We have designed a method for the assessment of trabecular bone mass (TBM) in a central portion of L4 by means of CT scanning. A total of 29 normal individuals of different ages from both sexes, and 19 hemodialysis patients were studied. 3 selected patients were also studied 1 year later. A good in vivo reproducibility was demonstrated in a dog after repositioning. A positive inverse correlation was observed in the control group between age and TBM supporting the reliability of this method. As reported by others in the postmortem bone mineral analysis of L4, a majority of patients (78.9%) showed a normal or high TBM. From a total of 5 patients with increased TBM only 2 showed radiological osteosclerosis, and 4 of them presented advanced subperiostal resorption suggesting a pathogenetic role of excessive circulating PTH in the genesis of osteosclerosis. A total of 4 had decreased TBM and only 2 of them showed radiological demineralization. 2 patients with decreased TBM, 1 of them under anticonvulsant therapy, experienced a considerable increase in the TBM after 1 year of 25OHD3 therapy. We conclude that this method can be an important help in the early detection and management of renal osteodystrophy.

© 1982 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Accepted: July 30, 1981
Published online: December 03, 2008
Issue release date: 1982

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF


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