Nephron

Original Paper

Sodium Kinetics Across Dialysis Membranes

Locatelli F. · Ponti R. · Pedrini L. · Costanzo R. · Di Filippo S. · Marai P. · Pozzi C.

Author affiliations

Divisione di Nefrologia e Dialisi, Ospedale di Lecco, Italia

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Nephron 1984;38:174–177

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Accepted: January 26, 1984
Published online: December 04, 2008
Issue release date: 1984

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF

Abstract

The kinetics of sodium across dialysis membranes were studied during diffusion and during convection utilizing cuprophan and cellulose hydrate membranes. During diffusion the changes in plasma water sodium concentration are correlated to the sodium concentration gradient between plasma water and dialysate but an increase also occurs when the gradient is annulled, due to the Donnan effect. During convection the plasma water sodium concentration increases during the passage through the dialyzer and the ultrafiltrate sodium concentration is significantly lower than the plasma water sodium concentration; this is due to the fact that the plasma proteins, as anions unable to cross the membrane, affect the kinetics of the sodium cations. Therefore, during diffusion the kinetics of sodium are mainly affected by the sodium concentration gradient and by the plasma protein concentration, while during convection the plasma protein concentration is the main factor affecting the kinetics of sodium.

© 1984 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Accepted: January 26, 1984
Published online: December 04, 2008
Issue release date: 1984

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF


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