Nephron

Original Paper

Prophylactic Treatment with Cimetidine after Renal Transplantation

Grekas D. · Nakos V. · Theocharides A. · Spanos P. · Arvanitakis C. · Tourkantonis A.

Author affiliations

First Medical Department, Renal and Transplantation Unit, University of Thessaloniki, Greece

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Nephron 1985;40:213–215

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Accepted: August 06, 1984
Published online: December 24, 2008
Issue release date: 1985

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF

Abstract

17 consecutive patients who underwent renal transplantation during the period 1979-1981 and were at risk of gastrointestinal hemorrhage were treated prophylactically with the histamine H2-blocker cimetidine without antacids. The incidence of gastrointestinal bleeding, the number of rejection episodes and graft survival were compared with 17 patients, who had received renal transplant during the period 1976–1978 and had not received cimetidine. The incidence of gastrointestinal hemorrhage was not reduced in the cimetidine-treated patients. In addition, cimetidine treatment neither increased the total number of rejection episodes nor changed the long-term graft survival. The results of this study indicate that cimetidine does not appear to be superior to antacids in the prevention of gastrointestinal bleeding in renal transplant recipients.

© 1985 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Accepted: August 06, 1984
Published online: December 24, 2008
Issue release date: 1985

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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