Digestive Surgery

Case Report

Effective Intra-Arterial Chemotherapy for Acinar Cell Carcinoma of the Pancreas

Ukei T.a · Okagawa K.a · Uemura Y.a · Miyauchi K.a · Kaneko T.a · Mizunoya S.a · Monden M.b

Author affiliations

aDepartment of Surgery, Kinki Central Hospital, Mutual Aid Association of Public School Teachers, Hyougo, and bDepartment of Surgery II, Osaka University School of Medicine, Osaka, Japan

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Dig Surg 1999;16:76–79

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Published online: February 12, 1999
Issue release date: 1999

Number of Print Pages: 4
Number of Figures: 2
Number of Tables: 0

ISSN: 0253-4886 (Print)
eISSN: 1421-9883 (Online)

For additional information: https://www.karger.com/DSU

Abstract

A 41-year-old man with a huge pancreatic tumor (acinar cell carcinoma) was treated by intra-arterial infusion chemotherapy with 5-fluorouracil (5-FU), mitomycin C (MMC) and cisplatin (CDDP). The tumor was significantly reduced, and he underwent a pancreaticoduodenectomy with complete excision of the tumor. Unfortunately multiple metastatic liver tumors were noted 5 months after resection. These tumors could also be markedly reduced by intra-arterial chemotherapy and the survival period was prolonged to 18 months. He suddenly died of sepsis but not from the pancreatic carcinoma. This case shows that intra-arterial infusion chemotherapy with 5-FU, MMC and CDDP can be an effective regimen for the treatment of acinar cell carcinoma of the pancreas.




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References

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Article / Publication Details

First-Page Preview
Abstract of Case Report

Published online: February 12, 1999
Issue release date: 1999

Number of Print Pages: 4
Number of Figures: 2
Number of Tables: 0

ISSN: 0253-4886 (Print)
eISSN: 1421-9883 (Online)

For additional information: https://www.karger.com/DSU


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Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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