Respiration
Pleural Effusion – Presenting Sign in Multiple MyelomaShoenfeld Y. · Pick A.I. · Weinberger A. · Ben-Bassat M. · Pinkhas J.Section of Clinical Immunology, The Rogoff-Wellcome Medical Research Institute, Department of Medicine ‘D’ and The Casper Institute of Pathology, Beilinson Medical Center, Petah-Tikva, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv
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Article / Publication Details
Received: June 14, 1977
Accepted: September 30, 1977
Published online: January 14, 2009
Issue release date: 1978
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)
For additional information: https://www.karger.com/RES
Abstract
A patient with multiple myeloma in whom recurrent right pleural effusion was the presenting sign of the disease is reported. An IgA (k) monoclonal component was found in both the pleural effusion and the serum. The bone marrow specimen was interpreted as typical for multiple myeloma and the pleural fluid contained numerous plasma cells. Treatment with cyclophosphamide was followed by clinical improvement and the disappearance of the pleural effusion. The clinical picture of symptomatic multiple myeloma (MM) is dominated by signs and symptoms attributed to bone marrow infiltration by the neoplastic cells and bone destruction [1]. Extraosseous involvement in MM is uncommon and pleural involvement is even more rare [2–4]. We describe a patient with MM in whom the presenting sign of the disease was a recurrent right pleural effusion which disappeared following treatment with cyclophosphamide.
© 1978 S. Karger AG, Basel
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Article / Publication Details
Received: June 14, 1977
Accepted: September 30, 1977
Published online: January 14, 2009
Issue release date: 1978
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)
For additional information: https://www.karger.com/RES
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