Respiration
Right Ventricular Failure in a Patient with Diabetic Neuropathy (Myopathy) and Central Alveolar HypoventilationSilverstein D. · Michlin B. · Sobel H.J. · Lavietes M.H.Department of Medicine-Pulmonary Division, College of Medicine and Dentistry of New Jersey, New Jersey Medical School and Department of Medicine and Pathology, East Orange Veterans Administration Hospital, East Orange, N.J., USA
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Article / Publication Details
Received: April 21, 1982
Accepted: February 21, 1983
Published online: January 15, 2009
Issue release date: 1983
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)
For additional information: https://www.karger.com/RES
Abstract
An unusual patient with hypoxemia, hypercapnia, and right ventricular failure is presented. Minimal skeletal muscle weakness, although present, cannot explain hypercapnia. Muscle biopsy revealed diabetic microangiopathy. Carbon dioxide stimulation demonstrated a diminished hypercapnic ventilatory response. The patient benefited from progesterone therapy. In this unusual patient, mild muscular weakness, caused by diabetes, and central alveolar hypoventilation have acted in synergism to cause abnormal ventilation and right ventricular failure.
© 1983 S. Karger AG, Basel
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Article / Publication Details
Received: April 21, 1982
Accepted: February 21, 1983
Published online: January 15, 2009
Issue release date: 1983
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)
For additional information: https://www.karger.com/RES
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