Respiration

Original Paper

Possible Gender Differences in the Effect of Exercise on Hypoxic Ventilatory Response

Regensteiner J.G.a · Pickett C.K.a · McCullough R.E.a · Weil J.V.a · Moore L.G.a,b

Author affiliations

aCardiovascular Pulmonary Research Laboratory, Health Sciences Center; and bDepartment of Anthropology, University of Colorado at Denver, Colo., USA

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Respiration 1988;53:158–165

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: April 22, 1987
Accepted: December 02, 1987
Published online: January 16, 2009
Issue release date: 1988

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)

For additional information: https://www.karger.com/RES

Abstract

Gender differences in resting ventilation and hypoxic ventilatory response (HVR) have been reported. Ventilation and HVR are closely related to changes in metabolic rate in men. However, it is unclear whether there is a comparable relationship between metabolic rate and ventilation or HVR in women. We studied 13 men and 12 women to determine whether exercise-induced increases in metabolic rate influenced ventilation, HVR, and hypercapnic ventilatory response (HCVR) differently in men and women. Minute ventilation per unit metabolic rate was higher (lower end-tidal PCO2) in women than men during rest and mild exercise. Resting HVR values were similar in men and women. With mild, exercise-induced increases in O2 consumption (24 ± 4% in men and 27 ± 2% in women, p = NS), HVR increased in men (p < 0.05) but not in women. Moderate exercise-induced increases in O2 consumption (313 ± 13% in men and 330 ± 13% in women, p = NS), raised hypoxic responses in both sexes. HCVR values were similar in men and women at rest and during mild exercise. Moderate exercise increased HCVR equally in the sexes. Thus the higher resting ventilation and lesser change in HVR during mild exercise suggested that women were less sensitive to mild metabolic rate stimulation than men.

© 1988 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: April 22, 1987
Accepted: December 02, 1987
Published online: January 16, 2009
Issue release date: 1988

Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0

ISSN: 0025-7931 (Print)
eISSN: 1423-0356 (Online)

For additional information: https://www.karger.com/RES


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