Digestion
Original Paper
Effect of Prostaglandin E1on Bile Flow in the RatNassar C.F. · Massad M. · Habbal Z.Departments of Physiology and Laboratory Medicine, Faculty of Medicine, American University of Beirut, Lebanon
Keywords: Prostaglandin E1Bile flow |
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Article / Publication Details
Received: August 24, 1983
Published online: January 28, 2009
Issue release date: 1984
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)
For additional information: https://www.karger.com/DIG
Abstract
The effect of intravenous administration of prostaglandin E1 on bile flow in the rat was investigated. PGE1 infused at concentrations of 4.5, 7.5 and 15 μg/kg body weight/min caused an initial increase in bile acid-independent bile flow rate which peaked within 30 min and was followed by a significant decrease (p < 0.01) below the control value. However, PGE1 administered intravenously at an infusion rate of 15 μg·kg-1•min-1 showed a significant decrease (p < 0.01) in bile acid-dependent bile flow rate.
© 1984 S. Karger AG, Basel
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Article / Publication Details
Received: August 24, 1983
Published online: January 28, 2009
Issue release date: 1984
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0012-2823 (Print)
eISSN: 1421-9867 (Online)
For additional information: https://www.karger.com/DIG
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