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Original Paper

Results of Splenectomy for Idiopathic Thrombocytopenic Purpura

Review of 72 Cases

Naouri A.a · Feghali B.a · Chabal J.a · Boulez J.a · Dechavanne M.b · Viala J.J.c · Tissot E.a

Author affiliations

aDepartment of General and Digestive Surgery, bHematology and Cytogenetic, Laboratory, and cDepartment of Hematology, Edouard Herriot Hospital, Lyon, France

Related Articles for ""

Acta Haematol 1993;89:200–203

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: July 22, 1992
Accepted: May 12, 1993
Published online: February 18, 2009
Issue release date: 1993

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)

For additional information: https://www.karger.com/AHA

Abstract

Seventy-two patients underwent splenectomy for idiopathic thrombocytopenic purpura between 1979 and 1990. Mean age at splenectomy was 36.4 years (range 11-73). Indications for splenectomy were corticodependence in 21 cases and resistance to steroids in 44 cases. Thirty-five patients had platelet kinetic studies by 51Cr alloplatelets; 22 of them had splenic sequestration. Hematologic results were evaluated on discharge, at 3 months and in the long term (median follow-up 5.4 years). We had no mortality, morbidity was seen in 7% of the cases. None of the patients suffered from secondary infectious complications. 89% had good results on discharge ( > 120 × 109/1), 72.6% at 3 months and 90% on long-term follow-up. Factors associated with good response to splenectomy included a high postoperative platelet count (more than 120 × 109/1 on discharge), younger age at the time of surgery, preoperative corticodependence and predominantly splenic sequestration.

© 1993 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: July 22, 1992
Accepted: May 12, 1993
Published online: February 18, 2009
Issue release date: 1993

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)

For additional information: https://www.karger.com/AHA


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