Acta Haematologica
Original Paper
Chromosomes and Surface Markers in Lymph Node Cells from 2 Patients with AILD and IBL-Like T-Cell LymphomaSadamori N.a · Jubashi T.a · Nishino K.a · Oyakawa Y.a · Tagawa M.a · Ikeda S.a · Ichimaru M.a · Yamada Y.b · Muta T.d · Kusano M.e · Matsuo T.caDepartment of Hematology, Atomic Disease Institute, bDepartment of Oncology, and cFirst Department of Pathology, Nagasaki University School of Medicine, Nagasaki; dDepartment of Internal Medicine, Omura General Hospital, Omura; eDepartment of Internal Medicine, Sasebo General Hospital, Sasebo, Japan
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Article / Publication Details
Received: June 15, 1987
Accepted: September 08, 1987
Published online: February 24, 2009
Issue release date: 1988
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
Abstract
Chromosomes and surface markers in lymph node cells from 2 patients with angioimmunoblastic lymphadenopathy associated with dysproteinemia (AILD) or immunoblastic lymphadenopathy (IBL) and with IBL-like T-cell lymphoma, respectively, were examined before treatment. In the patient with AILD, a small clone with chromosome abnormality was found in lymph node cells although a surface marker study failed to demonstrate monoclonality. In this patient, the clinical and cytogenetic findings suggested a subtype of lymphoma with a mild clinical course and a benign histological appearance. In the patient with IBL-like T-cell lymphoma, a high percentage of metaphases showed chromosome abnormalities such as ring chromosomes. The clinical, immunological and cytogenetic findings suggested an aggressive type of lymphoma, even though the histologic appearance was similar to that of IBL.
© 1988 S. Karger AG, Basel
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Article / Publication Details
Received: June 15, 1987
Accepted: September 08, 1987
Published online: February 24, 2009
Issue release date: 1988
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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