Acta Haematologica

Original Paper

Chromosomes and Surface Markers in Lymph Node Cells from 2 Patients with AILD and IBL-Like T-Cell Lymphoma

Sadamori N.a · Jubashi T.a · Nishino K.a · Oyakawa Y.a · Tagawa M.a · Ikeda S.a · Ichimaru M.a · Yamada Y.b · Muta T.d · Kusano M.e · Matsuo T.c

Author affiliations

aDepartment of Hematology, Atomic Disease Institute, bDepartment of Oncology, and cFirst Department of Pathology, Nagasaki University School of Medicine, Nagasaki; dDepartment of Internal Medicine, Omura General Hospital, Omura; eDepartment of Internal Medicine, Sasebo General Hospital, Sasebo, Japan

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Acta Haematol 1988;79:161–167

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: June 15, 1987
Accepted: September 08, 1987
Published online: February 24, 2009
Issue release date: 1988

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)

For additional information: https://www.karger.com/AHA

Abstract

Chromosomes and surface markers in lymph node cells from 2 patients with angioimmunoblastic lymphadenopathy associated with dysproteinemia (AILD) or immunoblastic lymphadenopathy (IBL) and with IBL-like T-cell lymphoma, respectively, were examined before treatment. In the patient with AILD, a small clone with chromosome abnormality was found in lymph node cells although a surface marker study failed to demonstrate monoclonality. In this patient, the clinical and cytogenetic findings suggested a subtype of lymphoma with a mild clinical course and a benign histological appearance. In the patient with IBL-like T-cell lymphoma, a high percentage of metaphases showed chromosome abnormalities such as ring chromosomes. The clinical, immunological and cytogenetic findings suggested an aggressive type of lymphoma, even though the histologic appearance was similar to that of IBL.

© 1988 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: June 15, 1987
Accepted: September 08, 1987
Published online: February 24, 2009
Issue release date: 1988

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)

For additional information: https://www.karger.com/AHA


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