Acta Haematologica
Original Paper
Ultrastructural Studies of an Unusual Variant of Congenital Dyserythropoietic Anaemia Type IIDewar C.L. · Lowenthal R.M.Department of Medicine, University of Tasmania Clinical School, Hobart, Tasmania
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Article / Publication Details
Received: December 06, 1979
Accepted: March 28, 1980
Published online: February 27, 2009
Issue release date: 1980
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
Abstract
Electron microscopy of a new variant of congenital dyserythropoietic anaemia type II has yielded several unexpected results. The remarkable features include the relatively high percentage of erythrocytes with peripheral cisternae, the involvement of all bone marrow precursor cells, and the presence of ultrastructural defects in the granulocytes and platelets and on the cell surface of the erythrocytes. Experiments with vinblastine showed that this drug was capable of producing (in vitro) strikingly similar ultrastructural defects in healthy erythrocytes.
© 1980 S. Karger AG, Basel
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Article / Publication Details
Received: December 06, 1979
Accepted: March 28, 1980
Published online: February 27, 2009
Issue release date: 1980
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
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