Acta Haematologica
Original Paper
Management of Nodular Sclerosis Hodgkin’s Disease Stage I, II A and B: Evidence for a Beneficial Effect of MOPP on the Relapse RateLauria F. · Baccarani M. · Babini L. · Emiliani E. · Fiacchini M. · Gobbi M. · Mazza P. · Sciascia R. · Tura S.Chair of Hematology and Radium Institute, University of Bologna, School of Medicine, Division of Hematology, St. Orsola’s University Hospital, Bologna
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Article / Publication Details
Received: January 15, 1979
Accepted: May 10, 1979
Published online: March 03, 2009
Issue release date: 1979
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
Abstract
85 patients with previously untreated Hodgkin’s disease with stage I, II A and B nodular sclerosis were treated. 31 of them with stage I and II A were submitted to radiotherapy alone. All are alive, but 9 of them (30%) relapsed. On the contrary, 35 patients with stage I and II A, and 19 with stage I, II and IIE B were submitted to radiotherapy followed by three courses of MOPP. All 54 patients are alive and relapse-free. No severe complication related to chemotherapy was observed. The analysis of results suggests that 3 courses of MOPP can significantly (p < 0.00025) reduce the relapse rate in patients with stage I and II nodular sclerosis, eligible for radiotherapy, without increasing morbidity.
© 1979 S. Karger AG, Basel
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Article / Publication Details
Received: January 15, 1979
Accepted: May 10, 1979
Published online: March 03, 2009
Issue release date: 1979
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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