Acta Haematologica

Original Paper

Management of Nodular Sclerosis Hodgkin’s Disease Stage I, II A and B: Evidence for a Beneficial Effect of MOPP on the Relapse Rate

Lauria F. · Baccarani M. · Babini L. · Emiliani E. · Fiacchini M. · Gobbi M. · Mazza P. · Sciascia R. · Tura S.

Author affiliations

Chair of Hematology and Radium Institute, University of Bologna, School of Medicine, Division of Hematology, St. Orsola’s University Hospital, Bologna

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Acta Haematol 1979;62:262–266

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 15, 1979
Accepted: May 10, 1979
Published online: March 03, 2009
Issue release date: 1979

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)

For additional information: https://www.karger.com/AHA

Abstract

85 patients with previously untreated Hodgkin’s disease with stage I, II A and B nodular sclerosis were treated. 31 of them with stage I and II A were submitted to radiotherapy alone. All are alive, but 9 of them (30%) relapsed. On the contrary, 35 patients with stage I and II A, and 19 with stage I, II and IIE B were submitted to radiotherapy followed by three courses of MOPP. All 54 patients are alive and relapse-free. No severe complication related to chemotherapy was observed. The analysis of results suggests that 3 courses of MOPP can significantly (p < 0.00025) reduce the relapse rate in patients with stage I and II nodular sclerosis, eligible for radiotherapy, without increasing morbidity.

© 1979 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 15, 1979
Accepted: May 10, 1979
Published online: March 03, 2009
Issue release date: 1979

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)

For additional information: https://www.karger.com/AHA


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