Acta Haematologica
Screening for Abnormal Hemoglobins in the Middle East: New Data on Hemoglobin S and the Presence of Hemoglobin C in Saudi ArabiaGelpi A.P. · King M.C.The Palo Alto Medical Clinic, Palo Alto, Calif.; Department of International Health and the G. W. Hooper Foundation, University of California Medical Center, San Francisco, Calif.
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Article / Publication Details
Published online: March 03, 2009
Issue release date: 1976
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
Abstract
48 of 391 apparently healthy adult Saudi males had an AS hemoglobin pattern on electrophoresis, four subjects had an S pattern, and two subjects AC. A dithionite screening test lacked sensitivity and specificity in detecting hemoglobin S under the conditions of this study. A sickle cell trait frequency of 0.123 evidenced by hemoglobin electrophoresis correlates closely with previous studies of hemoglobinopathies in Saudi Arabs. The presence of four subjects with sickle cell disease in the study group provides further evidence of the ‘benign’ nature of sickle cell disease in Saudi Arabia.
© 1976 S. Karger AG, Basel
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Article / Publication Details
Published online: March 03, 2009
Issue release date: 1976
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
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