Gerontology
Experimental Section
Influence of Growth State on Relationship between Nuclear Template Activity and in vitro ‘Ageing’Whatley S.A. · Hill B.T.Laboratories of Cellular Pathology and Cellular Chemotherapy, Imperial Cancer Research Fund, London
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Article / Publication Details
Received: July 08, 1979
Accepted: August 10, 1979
Published online: April 06, 2009
Issue release date: 1980
Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0
ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)
For additional information: https://www.karger.com/GER
Abstract
A reduction in nuclear template activity occurred in He 125 cell cultures only after the expression of a reduction in growth ability. This suggests that these alterations in template activity are terminal events occurring late in the culture life span. Both the rate of loss of template activity and its qualitative aspects were influenced by the growth state of the cultures compared. Therefore, these factors should be taken into account in the analyses of the relationship between in vitro ‘ageing’ and nuclear template activity.
© 1980 S. Karger AG, Basel
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Article / Publication Details
Received: July 08, 1979
Accepted: August 10, 1979
Published online: April 06, 2009
Issue release date: 1980
Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0
ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)
For additional information: https://www.karger.com/GER
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