Gerontology
Critical Review
Hydergine in Senile Mental ImpairmentLoew D.M. · Weil C.Research and Development, Sandoz Ltd., Basel, Switzerland
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Article / Publication Details
Received: June 09, 1981
Accepted: August 28, 1981
Published online: April 06, 2009
Issue release date: 1982
Number of Print Pages: 21
Number of Figures: 0
Number of Tables: 0
ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)
For additional information: https://www.karger.com/GER
Abstract
Among gerontopsychiatric drugs, Hydergine is pharmacologically characterized by agonist action at central dopamine and serotonin receptors. This review presents a summary of the results obtained with Hydergine in numerous controlled trials in patients with senile mental impairment. Assessment was carried out by means of a rating scale (mainly the Sandoz Clinical Assessment Geriatric, or SCAG, scale), psychometric tests (e.g. the Nuremberg Geriatric Inventory, or NGI), and the EEG. Hydergine also lowers serum prolactin, though a correlation with clinical improvement has not been established as yet. In the discussion, the need for objective, measurable and precise indicators in gerontopsychiatry is stressed.
© 1982 S. Karger AG, Basel
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Article / Publication Details
Received: June 09, 1981
Accepted: August 28, 1981
Published online: April 06, 2009
Issue release date: 1982
Number of Print Pages: 21
Number of Figures: 0
Number of Tables: 0
ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)
For additional information: https://www.karger.com/GER
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