Gerontology
Experimental Section
Connective Tissue in Aging LungAndreotti L. · Bussotti A. · Cammelli D. · Aiello E. · Sampognaro S.Istituto di Clinica Medica III, Università di Firenze, Italia
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Article / Publication Details
Received: August 16, 1982
Accepted: February 03, 1983
Published online: April 08, 2009
Issue release date: 1983
Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0
ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)
For additional information: https://www.karger.com/GER
Abstract
Collagen, elastin and structural glycoproteins were measured in 21 intact lungs taken at postmortem examination after sudden death from subjects aged from 15 to 83. The data were expressed as milligrams per cubic centimeter of lung peripheral parenchyma inflated and fixed at the standard pressure of 25 cm H2O to exclude the pitfall of referring to dried tissue weight. The volume/weight ratio of inflated dried lung parenchyma increased significantly with aging; likewise the collagen content decreased and so did the collagen/elastin ratio, while the elastin content did not show any significant correlation with age. The present findings indicate that biochemical, morphological and functional data on the senile lung agree well.
© 1983 S. Karger AG, Basel
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Article / Publication Details
Received: August 16, 1982
Accepted: February 03, 1983
Published online: April 08, 2009
Issue release date: 1983
Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0
ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)
For additional information: https://www.karger.com/GER
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