Pathophysiology of Haemostasis and Thrombosis
Original Paper
Investigations on Intravascular Coagulation in Liver Disease: Soluble Fibrin Monomer Complexes in Liver CirrhosisCoccheri S. · Palareti G. · Dalmonte P.R. · Poggi M. · Boggian O.Department of Angiology and Blood Coagulation of the Regional Hospital, Chair of Occupational Medicine, University of Bologna; and Division of Gastroenterology of the Ospedale Maggiore Bellaria, Bologna
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Article / Publication Details
Received: February 10, 1978
Accepted: July 11, 1978
Published online: April 16, 2009
Issue release date: 1979
Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0
ISSN: 1424-8832 (Print)
eISSN: 1424-8840 (Online)
For additional information: https://www.karger.com/PHT
Abstract
Soluble fibrin monomer complexes (SFMC) have been quantitated in 18 patients with liver cirrhosis by means of plasma gel filtration on an agarose column. The concentration of SFMC (as related to total fibrinogen) was increased in cirrhotic patients. The difference between controls and patients, as well as the difference between compensated and decompensated cirrhotic subjects, was statistically significant. Although these data, together with the results of heparin administration in one reported case, suggest intravascular coagulation, some alternative explanations should also be considered.
© 1979 S. Karger AG, Basel
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Article / Publication Details
Received: February 10, 1978
Accepted: July 11, 1978
Published online: April 16, 2009
Issue release date: 1979
Number of Print Pages: 11
Number of Figures: 0
Number of Tables: 0
ISSN: 1424-8832 (Print)
eISSN: 1424-8840 (Online)
For additional information: https://www.karger.com/PHT
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