Pathophysiology of Haemostasis and Thrombosis
Original Paper
Fatty Streaks and Fibrous Plaques in Human Aorta Show Increased Plasminogen Activator ActivitySmokovitis A. · Kokolis N. · Alexaki-Tzivanidou E.Department of Physiology, Faculty of Veterinary Medicine, Aristotelian University of Thessaloniki, Greece
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Article / Publication Details
Received: July 27, 1987
Accepted: November 27, 1987
Published online: April 23, 2009
Issue release date: 1988
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 1424-8832 (Print)
eISSN: 1424-8840 (Online)
For additional information: https://www.karger.com/PHT
Abstract
Marked changes of the plasminogen activator activity, plasmin inhibition, and plasminogen activator inhibition were found in fatty streaks and fibrous plaques compared to the normal intima of the human aorta. Plasminogen activator activity and plasmin inhibition showed the following pattern: fibrous plaques > fatty streaks > normal intima. Plasminogen activator inhibition showed the opposite pattern: normal intima > fatty streaks > fibrous plaques. The tissue-type, but not the urokinase-type, plasminogen activator was detected immunologically.
© 1988 S. Karger AG, Basel
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Article / Publication Details
Received: July 27, 1987
Accepted: November 27, 1987
Published online: April 23, 2009
Issue release date: 1988
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 1424-8832 (Print)
eISSN: 1424-8840 (Online)
For additional information: https://www.karger.com/PHT
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