Gerontology
Clinical Section
Tetanus in the Elderly: Is It Different from That in Younger Age Groups?Khajehdehi P. · Rezaian G.-R.Intensive Care Unit, Department of Internal Medicine, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
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Article / Publication Details
Published online: April 18, 1998
Issue release date: May – June
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 3
ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)
For additional information: https://www.karger.com/GER
Abstract
Our aims were to itemize the clinical features and the outcome of tetanus in the elderly, as well as any age and sex differences in its acquisition. Therefore, we compared the demographic and clinical data of 12 elderly (group 1) cases of tetanus with 69 middle-aged patients (group 2) and 12 children (group 3) suffering from the same disease. There was no significant difference between the site of entry and incubation period or in the clinical and paraclinical findings among the three groups of patients. Acute respiratory failure was found more commonly in group 1 than in groups 2 and 3 (p = 0.0167 and p = 0.0006, respectively). It was also more common in group 2 than in group 3 (p = 0.0140). A mild form of tetanus was more often detected in children than in middle-aged and elderly cases (p = 0.0213 and p = 0.0013, respectively). Severe tetanus was seen more often in group 1 than in groups 2 and 3 (p = 0.0167 and p = 0.0006, respectively). Despite this, the mortality rate was not statistically different among the three groups of patients. Females were affected much less frequently than males with a female:male ratio of 1:3 in all three age groups. Our results suggest that elderly patients are at higher risk of acquiring a more severe form of tetanus and the subsequent development of acute respiratory failure. In addition, the disease is more common in males of all age groups, and age and sex have no apparent effect on the outcome of patients with tetanus.
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References
- Richardson JP, Knight AL: The prevention of tetanus in elderly. Arch Intern Med 1991;151:1712–1717.
- Richardson JP, Knight AL: The management and prevention of tetanus. J Emerg Med 1993;11:737–742.
- Nandi SR, Ghosh SK: Tetanus in a 92-year-old man. Br J Clin Pract 1988;42:78–79.
- Shreve ST, Spivak B: Tetanus in a 74-year-old woman. J Am Geriatr Soc 1994;42:424–425.
- Weiss BP, Strassburg MA, Feeley JC: Tetanus and diphtheria immunity in an elderly population in Los Angeles Country. Am J Public Health 1983;73:802–804.
-
Jenkins MT, Luhn NR: Active management of tetanus. Anesthesiology 1962;23:690–709.
- Weinstein L: Tetanus. N Engl J Med 1973;289:1293–1296.
- Trujillo MJ, Castillo A, Espana J, Guevara P, Eganez H: Tetanus in the adult: Intensive care and management experience with 233 cases. Crit Care Med 1980;8:419–423.
-
Kerr JH, Corbett JL, Prys-Roberts C, Crampton Smith A, Spalding JMK: Involvement of the sympathetic nervous system in tetanus: Studies on 82 cases. Lancet 1968;ii:236–241.
-
Prys-Roberts C, Corbett JL, Kerr JH, Spalding JMK, Crampton Smith A: Treatment of sympathetic over-activity in tetanus. Lancet 1969;i:542–545.
-
Kloetzel K: Clinical patterns in severe tetanus. JAMA 1963;185:559–567.
-
Andrews J, Marcus A, Muirhead KM: A fatal case of tetanus: Treated by suxamethonium chloride, tracheotomy, and intermittent positive-pressure respiration. Lancet 1956;ii:652–653.
- Koblin BA, Townsend TR: Immunity to diphtheria and tetanus in inner-city women of childbearing age. Am J Public Health 1989;79:1297–1298.
-
Levine L, Wyman L: Survey of immunity by serologic methods: Results of three successive surveys of samples of the Massachusetts population for diphtheria and tetanus antitoxin. N Engl J Med 1965;272:23–26.
-
West JB: Other tests; in West JB (ed): Pulmonary Pathophysiology. Baltimore, Williams & Wilkins, 1982, pp 42–56.
- Rodrigues CJ, Rodrigues AJ Jr, Bohm GM: Effect of aging on muscle fibers and collagen content of the diaphragm: A comparison with the rectus abdominis muscle. Gerontology 1996;42:218–228.
Article / Publication Details
Published online: April 18, 1998
Issue release date: May – June
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 3
ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)
For additional information: https://www.karger.com/GER
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