Transfusion Medicine and Hemotherapy
Metabolic Changes of Patients with Acute Necrotizing PancreatitisRoth E.a · Zöch G.a · Mauritz W.b · Karner J.a · Funovics J.a · Sporn P.b · Fritsch A.aaFirst University Clinic of Surgery, Department of Experimental Surgery, Vienna bClinic of Anesthesiology Intensive Care Unit 1 University of Vienna, Austria
|
|
Log in to MyKarger to check if you already have access to this content.
KAB
Buy a Karger Article Bundle (KAB) and profit from a discount!
If you would like to redeem your KAB credit, please log in.
Save over 20% compared to the individual article price.
Article / Publication Details
Published online: May 26, 2009
Issue release date: 1986
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 1660-3796 (Print)
eISSN: 1660-3818 (Online)
For additional information: https://www.karger.com/TMH
Abstract
We carried out metabolic investigations of 26 patients with severe forms of acute pancreatitis which were evaluated by an organ score. We formed six groups from this data: survivors and deceased in the first week, the second week, and after a further two weeks of illness. The amino acid patterns in plasma and muscles deviated considerably from normal at all times in both the surviving and the deceased patients. In particular, changes in the concentrations of branched-chain amino acids and glutamine in the muscle tissue have a prognostic value. In the range two to four (normal range: above 20), the factor glutamine VAL + LEU + ILE characterizes a prefinal condition in non-survivors. This factor increased in patients recovering from the illness from 6 to values over 20. Non-survivors (NS) had higher plasma levels of glucose and glucagon compared to surviving patients. Plasma glucagon concentrations in NS reached levels up to 4,000 pg/mL at admission, which declined gradually to normal range during the course of the illness.
© 1986 S. Karger AG, Basel
Related Articles:
Article / Publication Details
Published online: May 26, 2009
Issue release date: 1986
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 1660-3796 (Print)
eISSN: 1660-3818 (Online)
For additional information: https://www.karger.com/TMH
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Get Permission
