Causes of Food-Induced Anaphylaxis in Italian Adults: A Multi-Centre StudyAsero R.a · Antonicelli L.b · Arena A.c · Bommarito L.d · Caruso B.e · Colombo G.g · Crivellaro M.f · De Carli M.h · Della Torre E.i · Della Torre F.i · Heffler E.d · Lodi Rizzini F.j · Longo R.k · Manzotti G.l · Marcotulli M.m · Melchiorre A.m · Minale P.n · Morandi P.o · Moreni B.m · Moschella A.p · Murzilli F.q · Nebiolo F.d · Poppa M.p · Randazzo S.r · Rossi G.s · Senna G.E.f
aAmbulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano, bServizio di Allergologia, Ospedali Riuniti, Ancona, cAmbulatorio di Allergologia, Azienda USL 5 di Messina, Messina, dAmbulatorio di Allergologia e Immunologia, Azienda Ospedaliera Ordine Mauriziano, Torino, eServizio di Chimica Clinica ed Ematologia, and fUO Allergologia, Azienda Ospedaliera, Verona, gAllergy and Immunology Department, IRCCS Fondazione San Raffaele del Monte Tabor, Milan, hDipartimento di Medicina Interna, Azienda Ospedaliero-Universitaria Santa Maria della Misericordia, Udine, iINRCA-IRCCS UOC Pneumologia Generale, UO Allergologia, Casatenovo, jSSVD Allergologia, Spedali Civili, Brescia, kAzienda Sanitaria Provinciale, Vibo Valentia, lAzienda Ospedaliera, Treviglio, mUO Allergologia, Azienda Ospedaliera, Desenzano del Garda, nDipartimento di Allergologia, Ospedale San Martino, Genova, oAmbulatorio di Allergologia, Azienda Ospedaliera Vimercate, Ospedale di Giussano, Giussano, pASL 14, Domodossola, qUO Allergologia, Ospedale SS Filippo e Nicola, Avezzano, rAmbulatorio di Allergologia, ASL 2, Caltanissetta, and sAmbulatorio Allergologico, AUSL, Reggio Emilia, Italy
Do you have an account?
- Rent for 48h to view
- Buy Cloud Access for unlimited viewing via different devices
- Synchronizing in the ReadCube Cloud
- Printing and saving restrictions apply
Rental: USD 8.50
Cloud: USD 20.00
Article / Publication Details
Background: Data about food-induced anaphylaxis in Italy are missing. Objective: It was the aim of this study to detect the main foods/food allergens causing anaphylaxis in Italy. Methods: The frequency of anaphylaxis and the relative importance of many offending foods were assessed in 1,110 adult patients with food allergy diagnosed by common criteria at 19 allergy centres scattered throughout Italy from 1 January to 31 December 2007. Results: Fifty-eight of 1,110 (5%) food-allergic patients experienced at least 1 episode of anaphylaxis. On average, they were older than other food-allergic patients (34 vs. 31 years; p < 0.05). The majority of anaphylactic episodes occurred in patients sensitized to lipid transfer protein (LTP; n = 19), followed by shrimp (n = 10), tree nuts (n = 9), legumes other than peanut (n = 4), and seeds (n = 2); peanut, spinach, celery, buckwheat, wheat, avocado, tomato, fish, meat, and Anisakis caused an anaphylactic reaction in single patients. Among LTP-hypersensitive patients, peach caused 13/19 anaphylactic episodes. Shrimp-allergic patients were significantly older than other patients with food-induced anaphylaxis (p < 0.05), whereas patients allergic to LTP experienced their anaphylactic episodes at a younger age (p < 0.001). The frequency of anaphylaxis among patients sensitized to LTP, shrimp or tree nuts did not differ between northern and central/southern Italy. Conclusion: LTP is the most important allergen causing food-induced anaphylaxis in Italy, peach being the most frequently offending food. Peanut-induced anaphylaxis seems very uncommon. Geographic and environmental differences both between Italy and other countries and within Italy seem to play a relevant role in the pattern of sensitization to foods.
© 2009 S. Karger AG, Basel
Article / Publication Details
Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.