Oncology

 

Mitogenic Stimulation of Lymphocytes in Cancer Patients

Reddy M.M. · Goh K.O. · Poulter C.

Author affiliations

University of Rochester and Monroe Community Hospital, Rochester, N.Y.

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Oncology 1975;32:47–51

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: June 09, 2009
Issue release date: 1975

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0030-2414 (Print)
eISSN: 1423-0232 (Online)

For additional information: https://www.karger.com/OCL

Abstract

Peripheral blood lymphocytes obtained from 16 controls, 16 untreated cancer patients and 15 cancer patients treated with irradiation were cultured with phytohemag-glutinin (PHA) and pokeweed mitogen (PWM). The cultures were terminated on 3 and 7 days of incubation, and mitotic rates were obtained. The mitotic rates of untreated cancer patients for both mitogens did not differ significantly from those of controls. However, the mitotic rate obtained for 3-day PHA culture of the radiation-treated cancer patients was significantly different from controls, whereas the 7-day mitotic rate stimulated by PWM was significantly lower than the untreated cancer patients and controls.

© 1975 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: June 09, 2009
Issue release date: 1975

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0030-2414 (Print)
eISSN: 1423-0232 (Online)

For additional information: https://www.karger.com/OCL


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