Neuroepidemiology

Methods in Neuroepidemiology

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Occurrence of Depression in Families with Frontotemporal Dementia: A Family History Study

Horstmann V.a · Gräsbeck A.b, c

Author affiliations

Departments of aHealth Sciences and bPsychogeriatrics and cSwedish National Institute of Health Care and Sciences, Lund University, Lund, Sweden

Corresponding Author

Vibeke Horstmann

Department of Health Sciences

Faculty of Medicine, Lund University

Box 157, SE–221 00 Lund (Sweden)

Tel. +46 46 222 1872, Fax +46 46 222 1959, E-Mail vibeke.horstmann@med.lu.se

Keywords: Frontotemporal dementiaDepressionCo-aggregationFamily history study

Related Articles for ""
Neuroepidemiology 2009;33:124–130
https://doi.org/10.1159/000226125

Abstract

Background: There are clinical similarities between frontotemporal dementia (FTD) and depression. The aim is to study co-aggregation of depression in families with FTD, indicating the existence of common aetiological factors. Methods: The study included 74 index patients with FTD and their 540 first-degree relatives above the age of 15 years. Occurrence of depression was studied at 3 different levels. Results: The incidence of depression in first-degree relatives of FTD patients was not higher than that of a general population. Occurrence of depression was not higher in families where parents had FTD compared to families with parents having no indications of FTD. Individuals with FTD had not suffered from depression to a greater extent than those without FTD. Conclusions: The hypothesis of a common aetiological factor of FTD and depression was not supported.

© 2009 S. Karger AG, Basel



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Article / Publication Details

First-Page Preview
Abstract of Methods in Neuroepidemiology

Received: February 01, 2009
Accepted: May 03, 2009
Published online: June 26, 2009
Issue release date: August 2009

Number of Print Pages: 7
Number of Figures: 2
Number of Tables: 4

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: https://www.karger.com/NED

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2009, Vol.33, No. 2

August 2009

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