The Passage of Maternal Dietary Proteins into Human Breast MilkKilshaw P.J.a · Cant A.J.b
aNutrition Department, National Institute for Research in Dairying, Shinfield; bDepartment of Child Health, St. George’s Hospital Medical School, London, UK
Do you have an account?
- Rent for 48h to view
- Buy Cloud Access for unlimited viewing via different devices
- Synchronizing in the ReadCube Cloud
- Printing and saving restrictions apply
Rental: USD 8.50
Cloud: USD 20.00
Samples of breast milk and serum were taken from 29 women at various stages of lactation before and after they had ingested 1 raw egg and half a pint of cow’s milk. The samples were analysed for cow’s milk and egg proteins using a solid-phase radioimmunoassay. β-Lactoglobulin, ovalbumin (OA) and ovomucoid were detected in breast milk from 10 out of 19, 13 out of 22 and 7 out of 9 women, respectively, in concentrations ranging from 110 pg/ml to 6.4 ng/ml. Maximum levels in breast milk were attained 4 or 6 h after ingestion and in serum 1–2 h earlier. The OA in breast milk was of normal molecular size (43,500 daltons) and indistinguishable from native OA in the radioimmunoassay. Gel filtration of whole breast milk or high molecular weight fractions at pH 2.6 failed to reveal additional OA, suggesting that immune complexes were not present. In serum, OA was detected both in its native form and in immune complexes. The possible significance of these antigens in the suckling infant is discussed.
© 1984 S. Karger AG, Basel
Article / Publication Details
Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.