Login to MyKarger

New to MyKarger? Click here to sign up.



Login with Facebook

Forgot your password?

Authors, Editors, Reviewers

For Manuscript Submission, Check or Review Login please go to Submission Websites List.

Submission Websites List

Institutional Login
(Shibboleth or Open Athens)

For the academic login, please select your country in the dropdown list. You will be redirected to verify your credentials.

Laboratory Investigation

Subthalamic Nucleus Location: Relationships between Stereotactic AC-PC-Based Diagrams and MRI Anatomy-Based Contours

Caire F.a, f · Ouchchane L.a, b · Coste J.a, c · Gabrillargues J.a, d · Derost P.e · Ulla M.e · Durif F.e · Lemaire J.-J.a, c

Author affiliations

aEquipe de Recherche en Signal et Imagerie Médicale, EA 3295 et bLaboratoire de Biostatistiques, Télématique et Traitement d’Images, Faculté de Médecine, Université Clermont 1, cService de Neurochirurgie A, dUnité de Neuroradiologie, Service de Radiologie A, et eService de Neurologie A, CHU Clermont-Ferrand, Hôpital G. Montpied, Clermont-Ferrand, et fService de Neurochirurgie, CHU Limoges, Hôpital Dupuytren, Limoges, France

Related Articles for ""

Stereotact Funct Neurosurg 2009;87:337–347

Do you have an account?

Login Information





Contact Information











I have read the Karger Terms and Conditions and agree.



Login Information





Contact Information











I have read the Karger Terms and Conditions and agree.



To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

CHF 38.00 *
EUR 35.00 *
USD 39.00 *

Select

KAB

Buy a Karger Article Bundle (KAB) and profit from a discount!

If you would like to redeem your KAB credit, please log in.


Save over 20% compared to the individual article price.
Learn more

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00


Select

Subscribe

  • Access to all articles of the subscribed year(s) guaranteed for 5 years
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select

* The final prices may differ from the prices shown due to specifics of VAT rules.

Article / Publication Details

First-Page Preview
Abstract of Laboratory Investigation

Received: February 17, 2009
Accepted: June 05, 2009
Published online: September 10, 2009
Issue release date: November 2009

Number of Print Pages: 11
Number of Figures: 6
Number of Tables: 3

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: https://www.karger.com/SFN

Abstract

Subthalamic nucleus (STN) targeting is classically performed based on AC-PC probabilistic position. Nevertheless, MRI allows direct visualization and targeting. We aimed to compare the position localized on MR images with standard stereotactic diagrams. The STN was manually contoured on MR images (22 Parkinson’s disease patients); boundaries were simplified in a schematic polygonal form. Front and lateral stereotactic diagrams were constructed according to Talairach and Benabid. We compared x, y and z coordinates of the geometrical center of MRI-based polygons and stereotactic diagrams (Wilcoxon matched-pairs tests). There was significant discordance between MRI-based polygons and AC-PC-based images. MRI shows the STN as more posterior, medial and slightly inferior.

© 2009 S. Karger AG, Basel


References

  1. Talairach J, David M, Tournoux P, et al: At-las d’anatomie stéréotaxique. Repérage radiologique indirect des noyaux gris centraux des régions mésencéphalo-sous-optiques et hypothalamiques de l’homme. Paris, Masson et Cie, 1957.
  2. Benabid AL, Koudsie A, Benazzouz A, Le Bas JF, Pollak P: Imaging of subthalamic nucleus and ventralis intermedius of the thalamus. Mov Disord 2002;17(suppl 3):S123–S129.
  3. Schaltenbrand G, Bailey P: Introduction to stereotaxis with an atlas of the human brain vol 2. Stuttgart, Thieme, 1959.
  4. Nowinski WL, Thirunavuukarasuu A, Benabid AL: The Cerefy® Clinical Brain Atlas. Stuttgart, Thieme, 2004.
  5. Nowinski WL, Belov D, Pollak P, Benabid AL: Statistical analysis of 168 bilateral subthalamic nucleus implantations by means of the probabilistic functional atlas. Neurosurgery 2005;57(4 Suppl):319–330.
    External Resources
  6. Bardinet E, Bhattacharjee M, Dormont D, Pidoux B, Malandain G, Schüpbach M, Ayache N, Cornu P, Agid Y, Yelnik J: A three-dimensional histological atlas of the human basal ganglia. 2. Atlas deformation strategy and evaluation in deep brain stimulation for Parkinson disease. J Neurosurg 2009;110:208–219.
  7. Stancanello J, Muacevic A, Sebastiano F, Modugno N, Cerviri P, Ferrigno G, Uggeri F, Romanelli P: 3T MRI evaluation of the accuracy of atlas-based subthlamic nucleus identification. Med Phys 2008;35:3069–3077.
  8. Andrade-Souza YM, Schwalb JM, Hamani C, Eltahawy H, Hoque T, Saint-Cyr J, Lozano AM: Comparison of three methods of targeting the subthalamic nucleus for chronic stimulation in Parkinson’s disease. Neurosurgery 2008;62(suppl 2):875–883.
    External Resources
  9. Lemaire JJ, Coste J, Ouchchane L, Caire F, Nuti C, Derost P, Cristini V, Gabrillargues J, Hemm S, Durif F, Chazal J: Brain mapping in stereotactic surgery: a brief overview from the probabilistic targeting to the patient-based anatomic mapping. Neuroimage 2007;37(suppl 1):S109–S115.
  10. Breit S, LeBas JF, Koudsie A, Schulz J, Benazzouz A, Pollak P, Benabid AL: Pretargeting for the implantation of stimulation electrodes into the subthalamic nucleus: a comparative study of magnetic resonance imaging and ventriculography. Neurosurgery 2006;58(suppl 1):ONS83–ONS95.
  11. Cuny E, Guehl D, Burbaud P, Gross C, Dousset V, Rougier A: Lack of agreement between direct magnetic resonance imaging and statistical determination of a subthalamic target: the role of electrophysiological guidance. J Neurosurg 2002;97:591–597.
  12. Saint-Cyr JA, Hoque T, Pereira LC, Dos- trovsky JO, Hutchison WD, Mikulis DJ, Abosch A, Sime E, Lang AE, Lozano AM: Localization of clinically effective stimulating electrodes in the human subthalamic nucleus on magnetic resonance imaging. J Neurosurg 2002;97:1152–1166.
  13. Lanotte MM, Rizzone M, Bergamasco B, Faccani G, Melcarne A, Lopiano L: Deep brain stimulation of the subthalamic nucleus: anatomical, neurophysiological, and outcome correlations with the effects of stimulation. J Neurol Neurosurg Psychiatry 2002;72:53–58.
  14. Voges J, Volkmann J, Allert N, Lehrke R, Koulousakis A, Freund HJ, Sturm V: Bilateral high-frequency stimulation in the subthalamic nucleus for the treatment of Parkinson disease: correlation of therapeutic effect with anatomical electrode position. J Neurosurg 2002;96:269–279.
  15. Hamel W, Fietzek U, Morsnowski A, Schrader B, Herzog J, Weinert D, Pfister G, Muller D, Volkmann J, Deuschl G, Mehdorn HM: Deep brain stimulation of the subthalamic nucleus in Parkinson’s disease: evaluation of active electrode contacts. J Neurol Neurosurg Psychiatry 2003;74:1036–1046.
  16. Herzog J, Fietzek U, Hamel W, Morsnowski A, Steigerwald F, Schrader B, Weinert D, Pfister G, Müller D, Mehdorn HM, Deuschl G, Volkmann J: Most effective stimulation site in subthalamic deep brain stimulation for Parkinson’s disease. Mov Disord 2004;19:1050–1054.
  17. Godinho F, Thobois S, Magnin M, Guenot M, Polo G, Benatru I, Xie J, Salvetti A, Garcia-Larrea L, Broussolle E, Mertens P: Subthalamic nucleus stimulation in Parkinson’s disease: anatomical and electrophysiological localization of active contacts. J Neurol 2006;253:1347–1355.
  18. Lemaire JJ, Coste J, Ouchchane L, Hemm S, Derost P, Ulla M, Siadoux S, Gabrillargues J, Durif F, Chazal J: MRI anatomical mapping and direct stereotactic targeting in the subthalamic region: functional and anatomical correspondence in Parkinson’s disease. Int J CARS 2007;2:75–85.
    External Resources
  19. McClelland S 3rd, Vonsattel JP, Garcia RE, Amaya MD, Winfield LM, Pullman SL, Yu Q, Fahn S, Ford B, Goodman RR: Relationship of clinical efficacy to postmortem-determined anatomic subthalamic stimulation in Parkinson syndrome. Clin Neuropathol 2007;26:267–275.
  20. Sun DA, Yu H, Spooner J, Tatsas AD, Davis T, Abel TW, Kao C, Konrad PE: Postmortem analysis following 71 months of deep brain stimulation of the subthalamic nucleus for Parkinson disease. J Neurosurg 2008;109:325–329.
  21. Lemaire JJ, Durif F, Boire JY, Debilly B, Irthum B, Chazal J: Direct stereotactic MRI location in the globus pallidus for chronic stimulation in Parkinson’s disease. Acta Neurochir 1999;141:759–766.
  22. Coste J, Ouchchane L, Sarry L, Derost P, Durif F, Gabrillargues J, Hemm S, Lemaire JJ: New electrophysiological mapping combined with MRI in parkinsonian’s subthalamic region. Eur J Neurosci 2009;29:1627–1633.
  23. Bejjani BP, Dormont D, Pidoux B, Yelnik J, Damier P, Arnulf I, Bonnet AM, Marsault C, Agid Y, Philippon J, Cornu P: Bilateral subthalamic stimulation for Parkinson’s disease by using three-dimensional stereotactic mag- netic resonance imaging and electrophysiological guidance. J Neurosurg 2000;92:615–625.
  24. Acar F, Miller JP, Berk MC, Anderson G, Burchiel KJ: Safety of anterior commissure- posterior commissure-based target calculation of the subthalamic nucleus in functional stereotactic procedures. Stereotact Funct Neurosurg 2007;85:287–291.
  25. Pollo C, Meuli R, Maeder P, Vingerhoets F, Ghika J, Villemure JG: STN DBS for Parkinson’s disease: MRI targeting using visible anatomical landmarks. Stereotactic Funct Neurosurg 2003;80:76–81.
  26. Giller CA, Babcock EE, Mendelsohn DB: Use of sagittal images for localization of the subthalamic nucleus. Technical note. J Neurosurg 2005;102:571–575.
  27. Slavin KV, Thulborn KR, Wess C, Nersesyan H: Direct visualization of the human subthalamic nucleus with 3T MR imaging. AJNR Am J Neuroradiol 2006;27:80–84.
  28. Patel NK, Khan S, Gill SS: Comparison of atlas- and magnetic-resonance-imaging-based stereotactic targeting of the subthalamic nucleus in the surgical treatment of Parkinson’s disease. Stereotact Funct Neurosurg 2008;86:153–161.
  29. Schuurman PR, de Bie RM, Majoie CB, Speelman JD, Bosch DA: A prospective comparison between three-dimensional magnetic resonance imaging and ventriculography for target-coordinate determination in frame-based functional stereotactic neurosurgery. J Neurosurg 1999;91:911–914.
  30. Rezai AR, Kopell BH, Gross RE, Vitek JL, Sharan AD, Limousin P, Benabid AL: Deep brain stimulation for Parkinson’s disease: surgical issues. Mov Disord 2006;21(suppl 14):S197–S218.
  31. Starr PA, Vitek JL, DeLong M, Bakay RA: Magnetic resonance imaging-based stereotactic localization of the globus pallidus and subthalamic nucleus. Neurosurgery 1999;44:303–313.
  32. Sterio D, Zonenshayn M, Mogilner AY, Rezai AR, Kiprovski K, Kelly PJ, Beric A: Neurophysiological refinement of subthalamic nucleus targeting. Neurosurgery 2002;50:58–67.
  33. Zonenshayn M, Rezai AR, Mogilner AY, Beric A, Sterio D, Kelly PJ: Comparison of anatomic and neurophysiological methods for subthalamic nucleus targeting. Neurosurgery 2000;47:282–292.
  34. Vayssiere N, Hemm S, Zanca M, Picot MC, Bonafe A, Cif L, Frerebeau P, Coubes P: Magnetic resonance imaging stereotactic target localization for deep brain stimulation in dystonic children. J Neurosurg 2000;93:784–790.
  35. Vayssière N, Hemm S, Cif L, Picot MC, Diakonova N, El Fertit H, Frerebeau P, Coubes P: Comparison of atlas- and magnetic resonance imaging-based stereotactic targeting of the globus pallidus internus in the performance of deep brain stimulation for treatment of dystonia. J Neurosurg 2002;96:673–679.
  36. Derost PP, Ouchchane L, Morand D, Ulla M, Llorca PM, Barget M, Debilly B, Lemaire JJ, Durif F: Is DBS-STN appropriate to treat severe Parkinson disease in an elderly population? Neurology 2007;68:1345–1355.
  37. Starr PA, Christine CW, Theodosopoulos PV, Lindsey N, Byrd D, Mosley A, Marks WJ Jr: Implantation of deep brain stimulators into the subthalamic nucleus: technical approach and magnetic resonance imaging-verified lead locations. J Neurosurg 2002;97:370–387.
  38. Sumanaweera TS, Adler JR Jr, Napel S, Glover GH: Characterization of spatial distortion in magnetic resonance imaging and its implications for stereotactic surgery. Neurosurgery 1994;35:696–703.
  39. Sumanaweera T, Glover G, Song S, Adler J, Napel S: Quantifying MRI geometric distortion in tissue. Magn Reson Med 1994;31:40–47.
  40. Walton L, Hampshire A, Forster DM, Kemeny AA: Stereotactic localization using magnetic resonance imaging. Stereotact Funct Neurosurg 1995;64(suppl 1):155–163.
    External Resources
  41. Walton L, Hampshire A, Forster DM, Kemeny AA: A phantom study to assess the accuracy of stereotactic localization, using T1-weighted magnetic resonance imaging with the Leksell stereotactic system. Neurosurgery 1996;38:170–176.
  42. Burchiel KJ, Nguyen TT, Coombs BD, Szumoski J: MRI distortion and stereotactic neurosurgery using the Cosman-Roberts-Wells and Leksell frames. Stereotact Funct Neurosurg 1996;66:123–136.
  43. Bourgeois G, Magnin M, Morel A, Sartoretti S, Huisman T, Tuncdogan E, Meier D, Jeanmonod D: Accuracy of MRI-guided stereotactic thalamic functional neurosurgery. Neuroradiology 1999;41:636–645.
  44. Magnotta VA, Gold S, Andreasen NC, Ehrhardt JC, Yuh WT: Visualization of subthalamic nuclei with cortex attenuated inversion recovery MR imaging. Neuroimage 2000;11:341–346.
  45. Hariz MI, Krack P, Melvill R, Jorgensen JV, Hamel W, Hirabayashi H, Lenders M, Wesslen N, Tengvar M, Yousry TA: A quick and universal method for stereotactic visualization of the subthalamic nucleus before and after implantation of deep brain stimulation electrodes. Stereotact Funct Neurosurg 2003;80:96–101.
  46. Dormont D, Ricciardi KG, Tande D, Parain K, Menuel C, Galanaud D, Navarro S, Cornu P, Agid Y, Yelnik J: Is the subthalamic nucleus hypointense on T2-weighted images? A correlation study using MR imaging and stereotactic atlas data. AJNR Am J Neuroradiol 2004;25:1516–1523.
  47. Lee C, Young B, Sanders MF: The role of the supramammillary commissure in MR localization of the subthalamic nucleus. Stereotact Funct Neurosurg 2006;84:193–204.
  48. Caire F, Derost P, Coste J, Bonny JM, Durif F, Frenoux E, Villeger A, Lemaire JJ: Stimulation sous-thalamique dans la maladie de Parkinson idiopathique: étude de la localisation des contacts effectifs. Neurochirurgie 2006;52:15–25.
  49. Lemaire JJ, Durif F, Debilly B, Blanc O, Chazal J: Deep brain stimulation in the subthalamic area for severe idiopathic Parkinson’s disease: location of plots in the peroperative phase and at the three month follow-up. XIVth International congress on Parkinson’s disease. Helsinki, 28/7-1-8 2001. Parkinson Relat Disord 2001;7(suppl):S80.
  50. Lemaire JJ, Caire F, Bony JM, Kemeny JL, Villéger A, Chazal J: Contribution of 4.7 T MRI in the analysis of MRI anatomy of the human subthalamic area. Acta Neurochir 2004;146:906–907.
  51. Rijkers K, Temel Y, Visser-Vandewalle V, Vanormelingen L, Vandersteen M, Adriansen P, Gelan J, Beuls EAM: The microenvironment of the subthalamic nucleus. J Neurosurg 2007;107:198–201.
  52. Hamani C, Richter EO, Andrade-Souza Y, Hutchison W, Saint-Cyr JA, Lozano AM: Correspondence of microelectrode mapping with magnetic resonance imaging for subthalamic nucleus procedures. Surg Neurol 2005;63:249–253.
  53. Danish SF, Jaggi JL, Moyer JT, Finkel L, Baltuch GH: Conventional MRI is inadequate to delineate the relationship between the red nucleus and subthalamic nucleus in Parkinson’s disease. Stereotact Funct Neurosurg 2006;84:12–18.
  54. Schlaier J, Schoedel P, Lange M, Winkler J, Warnat J, Dorenbeck U, Brawanski A: Reliability of atlas-derived coordinates in deep brain stimulation. Acta Neurochir (Wien) 2005;147:1175–1180.
  55. Ashkan K, Blomstedt P, Zrinzo L, Tisch S, Yousry T, Limousin-Dowsey P, Hariz MI: Variability of the subthalamic nucleus: the case for direct MRI guided targeting. Br J Neurosurg 2007;21:197–200.
  56. Richter EO, Hoque T, Halliday W, Lozano AM, Saint-Cyr JA: Determining the position and size of the subthalamic nucleus based on magnetic resonance imaging results in patients with advanced Parkinson disease. J Neurosurg 2004;100:541–546.
  57. Zhu XL, Hamel W, Schrader B, Weinert D, Hedderich J, Herzog J, Volkmann J, Deuschl G, Muller D, Mehdorn HM: Magnetic resonance imaging-based morphometry and landmark correlation of basal ganglia nuclei. Acta Neurochir (Wien) 2002;144:959–969.

Article / Publication Details

First-Page Preview
Abstract of Laboratory Investigation

Received: February 17, 2009
Accepted: June 05, 2009
Published online: September 10, 2009
Issue release date: November 2009

Number of Print Pages: 11
Number of Figures: 6
Number of Tables: 3

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: https://www.karger.com/SFN


Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.