Chemotherapy

Experimental Chemotherapy

Relation of Arginine-Lysine Antagonism to Herpes simplex Growth in Tissue Culture

Griffith R.S. · DeLong D.C. · Nelson J.D.

Author affiliations

Lilly Laboratory for Clinical Research and Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Ind., USA

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Chemotherapy 1981;27:209–213

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Article / Publication Details

First-Page Preview
Abstract of Experimental Chemotherapy

Published online: September 08, 2009
Issue release date: 1981

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0009-3157 (Print)
eISSN: 1421-9794 (Online)

For additional information: https://www.karger.com/CHE

Abstract

In the studies conducted, arginine deficiency suppressed herpes simplex virus replication in tissue culture. Lysine, an analog of arginine, as an antimetabolite, antagonized the viral growth-promoting action of arginine. The in vitro data may be the basis for the observation that patients prone to herpetic lesions and other related viral infections, particularly during periods of stress, should abstain from arginine excess and may also require supplemental lysine in their diet.

© 1981 S. Karger AG, Basel




Article / Publication Details

First-Page Preview
Abstract of Experimental Chemotherapy

Published online: September 08, 2009
Issue release date: 1981

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0009-3157 (Print)
eISSN: 1421-9794 (Online)

For additional information: https://www.karger.com/CHE


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