Chemotherapy
Microbiology
Comparative in vitro Activity of Chloramphenicol and Thiamphenicol against Haemophilus Influenzae, Neisseria Gonorrhoeae and the Typhoid and Paratyphoid BacilliNg W.S.a · Chau P.Y.bDepartments of aExtra-Mural Studies and bMicrobiology, University of Hong Kong, Hong Kong
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Article / Publication Details
Published online: September 08, 2009
Issue release date: 1982
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0009-3157 (Print)
eISSN: 1421-9794 (Online)
For additional information: https://www.karger.com/CHE
Abstract
Chloramphenicol and thiamphenicol were tested by the agar dilution method against 105 Salmonella typhi, 15 S. paratyphi A, 6 S. paratyphi B, 8 S. paratyphi C, 57 Haemophilus influenzae and 60 Neisseriagonorrhoeae strains. The two drugs showed similar in vitro activity against strains of H. influenzae and N. gonorrhoeae irrespective of their β-lactamase production. In contrast, while all the tested isolatels of typhoid and paratyphoid fever Salmonella were susceptible to chloramphenicol, most of these strains showed resistance to thiamphenicol with MICs > 8 µg/ml. The significance of these findings are discussed.
© 1982 S. Karger AG, Basel
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Article / Publication Details
Published online: September 08, 2009
Issue release date: 1982
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0009-3157 (Print)
eISSN: 1421-9794 (Online)
For additional information: https://www.karger.com/CHE
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