Chemotherapy

Microbiology

Comparative in vitro Activity of Carumonam (Ro 17–2301/AMA-1080), a New Monobactam, and Ceftriaxone against Aerobic or Facultative Gram-Negative Isolates

Barclay C.A. · Iribarren M.A. · Goldberg M. · Traballi C.A. · Casellas J.M.

Author affiliations

División Investigatión. Productos Roche SAQ e I, Cátedra de Infectologia y Microbiologia Clínica, Universidad Católica, Buenos Aires, Argentina

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Chemotherapy 1987;33:165–171

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Article / Publication Details

First-Page Preview
Abstract of Microbiology

Published online: September 09, 2009
Issue release date: 1987

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 0009-3157 (Print)
eISSN: 1421-9794 (Online)

For additional information: https://www.karger.com/CHE

Abstract

Carumonam (Ro 17–2301/AMA-1080) is a new monobactam antibiotic. A comparative in vitro evaluation with ceftriaxone was undertaken against 153 gram-negative clinical aerobic or facultative bacteria, both producers and nonproducers of β-lactamase. Results indicated that carumonam had an enhancement of activity for Pseudomonas aeruginosa, Klebsiella oxytoca, Citrobacter freundii and Enterobacter cloacae and parallelled that of ceftriaxone against Escherichia coli, Klebsiella pneumoniae, Proteus spp. and Serratia marcescens. It can be concluded that carumonam could be an alternative of interest for the treatment of patients with infections due to gram-negative strains presumably or proven to be multiresistant.

© 1987 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Microbiology

Published online: September 09, 2009
Issue release date: 1987

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0

ISSN: 0009-3157 (Print)
eISSN: 1421-9794 (Online)

For additional information: https://www.karger.com/CHE


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