Chemotherapy
Aztreonam: New Developments and Current Perspectives
Aztreonam in the Treatment of Aerobic, Gram-Negative Bacillary Infections in Pediatric PatientsTrujillo H.a · Harry N.b · Arango A.c · Benitez G.c · Restrepo F.c · Mejia de R. G.I.a · Castrillón de P. A.L.aaCorporation para Investigaciones Biológicas; Pablo Tobón Uribe Hospital; bGeneral Hospital; cMedellin Children’s Hospital, Medellin, Colombia
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Article / Publication Details
Published online: September 09, 2009
Issue release date: 1989
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 0009-3157 (Print)
eISSN: 1421-9794 (Online)
For additional information: https://www.karger.com/CHE
Abstract
Aztreonam was administered to 20 children diagnosed as having any of the following infections: urinary tract infection, pneumonia, meningitis, and abscess of the appendix. Haemophilus influenzae, Escherichia coli, and Klebsiellapneumoniae were isolated. The minimum inhibitory concentrations of aztreonam for these bacteria ranged from 0.03 to 0.5 μg/ml. All patients were clinically and bacteriologically cured within 5–16 days of treatment. Six months after completion of therapy, patients who had had meningitis appeared to be free of any neurologic sequelae. The antibiotic was well tolerated by all patients.
© 1989 S. Karger AG, Basel
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Article / Publication Details
Published online: September 09, 2009
Issue release date: 1989
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0
ISSN: 0009-3157 (Print)
eISSN: 1421-9794 (Online)
For additional information: https://www.karger.com/CHE
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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