Neonatology

 

Perinatal Primate Parathyroid Hormone Metabolism

Fleischman A.R. · Lerman S. · Oakes G.K. · Epstein M.F. · Chez R.A. · Mintz D.H.

Author affiliations

Pregnancy Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md., and Department of Medicine, University of Miami School of Medicine, Miami, Fla.

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Biol Neonate 1975;27:40–49

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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: September 16, 2009
Issue release date: 1975

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: https://www.karger.com/NEO

Abstract

Near-term fetal and neonatal parathyroid gland function has been studied in the Rhesus monkey. Fetal serum ionized calcium (Ca++) levels are significantly greater than simultaneously obtained maternal levels. Fetal serum parathyroid hormone (PTH) was undetectable both in the basal state and in association with EDTA-induced fetal hypocalcemia. Induced maternal hypocalcemia was associated with increased maternal serum PTH levels and no change in fetal basal serum Ca++ or PTH levels. Only a minimal decrease in simian neonatal serum Ca++ occurred over the first 48 h of life. Normal adult levels of serum PTH were present as early as 6 h of neonatal life. Induced hypocalcemia at 12 h of age resulted in a significant increase in serum PTH levels.

© 1975 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Paper

Published online: September 16, 2009
Issue release date: 1975

Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: https://www.karger.com/NEO


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