Neonatology
Cord and Maternal Serum Meperidine Concentrations and Clinical Status of the InfantRothberg R.M. · Rieger C.H.L. · Hill J.H. · Danielson J. · Matadial L.Departments of Pediatrics and Obstretrics and Gynecology, Pritzker School of Medicine, University of Chicago, Chicago, Ill.
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Article / Publication Details
Published online: September 17, 2009
Issue release date: 1978
Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0
ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)
For additional information: https://www.karger.com/NEO
Abstract
The possible relationship between the use of meperidine during labor and fetal or neonatal distress was investigated by correlating clinical parameters with maternal and cord serum concentrations of meperidine. The serum concentration of meperidine was determined by a radioimmunoassay which is 100-fold more sensitive than previously employed techniques and can detect as little as 0.02 nmol meperidine/ml. The incidence of fetal or neonatal depression following meperidine administration was higher (6 of 17 infants) than in a control group but no correlation between suppression and the route of meperidine administration or the serum meperidine concentrations at the time of delivery was found.
© 1978 S. Karger AG, Basel
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Article / Publication Details
Published online: September 17, 2009
Issue release date: 1978
Number of Print Pages: 10
Number of Figures: 0
Number of Tables: 0
ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)
For additional information: https://www.karger.com/NEO
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