Neonatology
Review
Plasma Calcium Control in the Rat Fetus. III. Influence of Alterations in Maternal Plasma Calcium on Fetal Plasma Calcium LevelIII. Influence of Alterations in Maternal Plasma Calcium on Fetal Plasma Calcium Level Groupe ‘Hormones du Calcium et Développement’, Université Pierre et Marie Curie, Paris, France
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Article / Publication Details
Published online: September 24, 2009
Issue release date: 1985
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)
For additional information: https://www.karger.com/NEO
Abstract
Acute maternal alterations in plasma calcium were used as an indirect mean to study the placental transfer of calcium in thyroparathyroidectomized (TPTX) pregnant rats. Calcium infusions to normal or TPTX females showed in both cases a saturation mechanism reflected on fetal plasma calcium. With TPTX mothers saturation curves of the fetal plasma calcium were similar whether fetuses were decapitated (deprived of brain, hypophysis, and thyroparathyroid complex) or intact. Increments in fetal plasma calcium were 4-fold higher in TPTX mothers (∼2.5mg/dl), and 2-fold higher in thyroidectomized (TX) mothers (∼0.5 mg/dl). From the whole results, it appeared that increments in fetal plasma calcium secondary to maternal calcium infusion were probably related to the basal plasma calcium in the fetus, and not to the hormonal deficiency of the mother.
© 1985 S. Karger AG, Basel
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Article / Publication Details
Published online: September 24, 2009
Issue release date: 1985
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)
For additional information: https://www.karger.com/NEO
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