Dermatology

Proceedings of the Tricontinental Symposium on Autoimmune Skin Diseases

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A Retrospective Analysis of Tissue-Fixed Immunoreactants from Skin Biopsies Maintained in Michel’s Medium

Vaughan Jones S.A. · Salas J. · McGrath J.A. · Palmer I. · Bhogal B.S. · Black M.M.

Author affiliations

Department of Immunofluorescence, St. John’s Institute of Dermatology, London, UK

Corresponding Author

Dr. S.A. Vaughan Jones, Department of Immunofluorescence, St. John’s Institute of Dermatology (UMDS), St. Thomas’ Hospital, London SE1 7EH (UK)

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Dermatology 1994;189:131–132

Abstract

656 skin biopsies with positive direct immunofluorescence from the UK and overseas were studied over a 2-year period. The length of time biopsies had remained in Michel’s medium at pH 7.0 in various diseases (pemphigoid, pemphigus, linear IgA disease, epidermolysis bullosa acquisita, lupus erythematosus, vasculitis, amyloid, lichen planus and dermatitis herpetiformis) was analysed. We concluded that direct immunofluorescence remained positive at 6 months and that Michel’s medium is a reliable long-term maintenance medium for skin biopsies.

© 1994 S. Karger AG, Basel




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Article / Publication Details

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Abstract of Proceedings of the Tricontinental Symposium on Autoimmune Skin Diseases

Published online: October 07, 2009
Issue release date: 1994

Number of Print Pages: 2
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: https://www.karger.com/DRM


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