Dermatology

Clinical and Laboratory Investigation

Genetic Polymorphisms in HLA-A, -B, -C and -DR Antigens in Japanese Patients with Palmoplantar Pustulosis

Torii H.a · Nakagawa H.a · Ishibashi Y.a · Tokunaga K.b · Juji T.b

Author affiliations

aDepartment of Dermatology and bBlood Transfusion Service, Faculty of Medicine, University of Tokyo, Japan

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Dermatology 1994;188:290–292

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Article / Publication Details

First-Page Preview
Abstract of Clinical and Laboratory Investigation

Received: January 29, 1993
Accepted: June 18, 1993
Published online: October 07, 2009
Issue release date: 1994

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: https://www.karger.com/DRM

Abstract

Genetic polymorphisms in HLA-A, -B, -C and -DR antigens were investigated in 78 unrelated Japanese patients with palmoplantar pustulosis (PPP) and compared with a total of 472 normal persons. Only HLA-DR9 showed a significantly increased frequency among all HLA antigens investigated (χ2 = 11.57, p < 0.001). It is suggested that major histocompatibility complex class II antigens including HLA-DR antigen may determine the susceptibility to PPP and PPP may be a distinct disease entity from psoriasis.

© 1994 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Clinical and Laboratory Investigation

Received: January 29, 1993
Accepted: June 18, 1993
Published online: October 07, 2009
Issue release date: 1994

Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: https://www.karger.com/DRM


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