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Mini Review

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Prostatic Ductal Adenocarcinoma: A Mini Review

Epstein J.I.

Author affiliations

Departments of Pathology, Urology, and Oncology, The Johns Hopkins Hospital, Baltimore, Md., USA

Corresponding Author

Prof. Jonathan I. Epstein

Departments of Pathology, Urology, and Oncology, The Johns Hopkins Hospital

600 N. Wolfe Street

Baltimore, MD 21287 (USA)

Tel. +1 410 955 5043, Fax +1 410 955 0115, E-Mail jepstein@jhmi.edu

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Med Princ Pract 2010;19:82–85

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Prostatic ductal adenocarcinomas may arise either in large primary periurethral prostatic ducts or in the peripheral prostatic ducts. Ductal adenocarcinomas are composed of tall columnar cells arranged in cribriform, papillary, solid, single glands, and PIN-like patterns. Other than the prostatic intraepithelial neoplasia (PIN)-like ductal pattern, which behaves like Gleason pattern 3, ductal adenocarcinoma is comparable to Gleason pattern 4 prostate cancer. Ductal adenocarcinoma can have a patchy basal cell layer and typically expresses prostate-specific antigen (PSA) immunohistochemically. Mimickers of ductal adenocarcinoma include prostatic urethral polyps, hyperplastic benign prostate glands, high-grade PIN, colorectal adenocarcinoma, and papillary urothelial carcinoma.

© 2009 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Mini Review

Received: May 17, 2009
Accepted: May 21, 2009
Published online: December 09, 2009
Issue release date: December 2009

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 1011-7571 (Print)
eISSN: 1423-0151 (Online)

For additional information: http://www.karger.com/MPP

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