Caries Research
Animal Studies
Macroscopic Appearance, Microhardness and Microradiographic Characteristics of Experimentally Produced Fluorotic Lesions in Sheep EnamelSuckling G.W. · Purdell-Lewis D.Dental Research Unit, MRC of NZ, Wellington, New Zealand; University of Groningen, Dental School, Groningen, The Netherlands
Keywords: Ameloblast activityEnamelFluorosisSheep |
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Article / Publication Details
Published online: November 17, 2009
Issue release date: 1982
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)
For additional information: https://www.karger.com/CRE
Abstract
Fluorotic lesions resembling those seen in human teeth were produced experimentally in the unerupted enamel of the central incisor teeth of 3 sheep by daily dosing for 21 days with 2, 4 or 6 mg fluoride/kg body weight. Opacities, both superficial and extending to the amelodentinal junction, horizontal lines and pits were seen on the specimens. A comparison between the sheep with the lowest and highest dosing showed that, at these fluoride levels and given for a relatively short period of tooth development, there was no clear correlation between fluoride intake and the type of fluorosis found. The opacities and the bases of the scattered pits showed consistently lower hardness values than the surrounding enamel and in addition, the mineral content of the opacities was significantly lower than that of the control enamel. These findings support the theory that fluorotic lesions may be both pre-eruptive or post-eruptive (traumatic) in origin.
© 1982 S. Karger AG, Basel
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Article / Publication Details
Published online: November 17, 2009
Issue release date: 1982
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)
For additional information: https://www.karger.com/CRE
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